Evidence map›Paper›PMID 40197929›Full record

Observational studyBrazilian oral research2025

Comorbidities in people living with HIV/AIDS and their impact on outpatient dental care.

Maria Fernanda Bartholo, Jefferson Rocha Tenório, Natália Silva Andrade, Cristiane Barbosa Silveira, Karem López Ortega, Fabiana Martins, Marina Gallottini

Abstract readObservational Study
In one paragraph

Observational study in Brazilian oral research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Fernanda BartholoUniversidade de São Paulo - USP, Special Care Dentistry Center, Department of Stomatology, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3447-2589
Jefferson Rocha TenórioUniversidade Federal do Rio de Janeiro - UFRJ, School of Dentistry Department of Pathology and Oral Diagnosis, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0002-6986-9148
Natália Silva AndradeUniversidade Federal do Sergipe - UFS, School of Dentistry, Department of Dentistry, São Cristóvão, SE, Brazil.ORCID http://orcid.org/0000-0001-5945-8401
Cristiane Barbosa SilveiraUniversidade de São Paulo - USP, Special Care Dentistry Center, Department of Stomatology, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6349-2848
Karem López OrtegaUniversidade de São Paulo - USP, Special Care Dentistry Center, Department of Stomatology, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-9573-2858
Fabiana MartinsUniversidade de São Paulo - USP, Special Care Dentistry Center, Department of Stomatology, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4352-7959
Marina GallottiniUniversidade de São Paulo - USP, Special Care Dentistry Center, Department of Stomatology, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6071-5110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to estimate the prevalence of comorbidities among people living with HIV/AIDS (PLWHIV) attending a dental outpatient clinic and discuss the impact of these comorbidities on dental management. A cross-sectional observational study evaluated 238 PLWHIV attending a specialized dental outpatient clinic in Brazil. We collected sociodemographic data, self-reported and physician-diagnosed comorbidities, hemogram results, CD4+ T cell count, viral load, use of combined antiretroviral therapy (cART), and information on harmful habits. The most prevalent comorbidities were sexually transmitted infections (STIs) (116/238; 48.7%), psychiatric disorders (105/238; 44.1%), and lipodystrophy (97/238; 40.8%). Men were more likely to have STIs (OR 4.0) and tuberculosis (OR: 2.5) (p < 0.05). Age ≥ 50 years increased the risk of diabetes mellitus by 2.6 times (p < 0.05). The risk of lipodystrophy (OR: 2.99, 95%CI 1.44-6.19) and psychiatric disorders (OR: 2.13, 95%CI 1.01-4.47) was greater in those who had been diagnosed with HIV for more than 20 years. In summary, psychiatric disorders and severe hematological alterations, such as anemia and neutropenia, are significant comorbidities that may limit dental treatment of HIV-positive patients. These findings underscore the need for integrated medical and dental care to address the complex health needs of PLWHIV.

Indexed as

Dental CareDental Care for Chronically IllHIV InfectionsAcquired Immunodeficiency SyndromeAdultAgedAge FactorsAmbulatory CareBrazilCD4 Lymphocyte CountComorbidityCross-Sectional StudiesFemaleHumansMaleMental Disorders

Identifiers

PMID40197929
PMCPMC11970520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.