Evidence map›Paper›PMID 40197919›Full record

ArticleBrazilian dental journal2025

Brazilian red propolis as a potential antimicrobial additive in orthodontic primers.

João Marcos Spessoto Pingueiro, Murilo Fernando Neuppmann Feres, Carla Cristina Macedo Vaz-Monteiro, Helen Karine Vieira-Silva, Gustavo Quilles Vargas, Larissa Matias Malavazi, Pedro Luiz Rosalen, Jamil Awad Shibli, Marina Guimarães Roscoe, Bruno Bueno-Silva

Abstract read
In one paragraph

Article in Brazilian dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

João Marcos Spessoto PingueiroDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.
Murilo Fernando Neuppmann FeresDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.ORCID 0000-0002-7185-544X
Carla Cristina Macedo Vaz-MonteiroDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.ORCID 0009-0002-4500-2002
Helen Karine Vieira-SilvaDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.
Gustavo Quilles VargasDepartment of Bioscience, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.ORCID 0009-0007-2383-009X
Larissa Matias MalavaziDepartment of Bioscience, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.ORCID 0009-0002-3552-5256
Pedro Luiz RosalenDepartment of Bioscience, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.ORCID 0000-0003-0812-4027
Jamil Awad ShibliDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.ORCID 0000-0003-1971-0195
Marina Guimarães RoscoeDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.ORCID 0000-0002-1670-4649
Bruno Bueno-SilvaDental Research Division, School of Dentistry, Guarulhos University, Guarulhos, São Paulo, Brazil.ORCID 0000-0003-3275-5910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effect of adding ethanolic extract of red propolis (EERP) on antimicrobial activity, polymerization kinetics (PK), degree of conversion (DC), and shear bond strength (SBS) of the orthodontic adhesive system. Transbond XT Primer was the control group (G1). The experimental adhesives contained 3.25 mg/mL (G2) and 6.50 mg/mL (G3) EERP. Minimum inhibitory concentration and biofilm assay against Streptococcus mutans, and bacterial and exopolysaccharide (EPS) evaluation by confocal laser scanning microscope were performed. PK and DC were evaluated by Fourier Transform Infrared Spectroscopy. The bracket-tooth SBS was evaluated by a universal testing machine. Both antimicrobial and SBS results were analyzed by ANOVA and Tukey's post-hoc test (p<0.05). PK and DC data were submitted to ANOVA and Bonferroni post-hoc test. G3 presented better antimicrobial activity, inhibiting more than 95% of planktonic S. Mutans, 25% of biofilm dry-weight, and 50% of EPS production (p<0.05). PK was different among the groups. DC after 40 seconds of photoactivation ranged from 68.62% for G1 to 76.85% for G2 (p<0.05). SBS data was not presented as statistically significant (p>0.05). Transbond XT Primer modified with 6.5 mg/mL EERP demonstrated antimicrobial activity with no reduction of the bracket-tooth SBS. Propolis-modification did not influence the physic-chemical properties of the orthodontic adhesive.

Indexed as

Anti-Infective AgentsOrthodontic BracketsPropolisBiofilmsBrazilMaterials TestingMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredStreptococcus mutansAnti-Infective AgentsPropolis

Identifiers

PMID40197919
PMCPMC11981592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.