Evidence map›Paper›PMID 40197900›Full record

ArticleRevista brasileira de epidemiologia = Brazilian journal of epidemiology2025

Factors associated with the interruption of antiretroviral therapy among people living with HIV/AIDS in Brazilian municipalities between 2019 and 2022.

Ana Paula da Cunha, Jurema Corrêa da Mota, Marly Marques da Cruz, Raquel Miranda, Liza Rosso, Mariele Kruppa, Juliane Santos, Andreia Souza Pinto da Silva, Giordana Faccin, Caroline Schweitzer and 2 more

Abstract read
In one paragraph

Article in Revista brasileira de epidemiologia = Brazilian journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ana Paula da CunhaFundação Oswaldo Cruz, Sergio Arouca National School of Public Health - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0002-1400-1472
Jurema Corrêa da MotaFundação Oswaldo Cruz, Institute of Scientific and Technological Communication and Information on Health - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0002-5007-1590
Marly Marques da CruzFundação Oswaldo Cruz, Sergio Arouca National School of Public Health - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0002-4061-474X
Raquel MirandaFundação Oswaldo Cruz, Sergio Arouca National School of Public Health - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0002-7668-7633
Liza RossoSecretaria Municipal da Saúde de Curitiba - Curitiba (PR), Brazil.ORCID http://orcid.org/0009-0001-1258-191X
Mariele KruppaSecretaria Municipal da Saúde de Curitiba - Curitiba (PR), Brazil.ORCID http://orcid.org/0009-0009-6353-1224
Juliane SantosSecretaria Municipal da Saúde de Curitiba - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0003-2898-8914
Andreia Souza Pinto da SilvaSecretaria Municipal de Saúde de Campo Grande - Campo Grande (MS), Brazil.ORCID http://orcid.org/0009-0001-4839-143X
Giordana FaccinSecretaria Municipal de Saúde de Campo Grande - Campo Grande (MS), Brazil.ORCID http://orcid.org/0009-0007-1214-3868
Caroline SchweitzerSecretaria Municipal de Saúde de Florianópolis - Florianópolis (SC), Brazil.ORCID http://orcid.org/0000-0001-7006-1317
Ronaldo ZontaSecretaria Municipal de Saúde de Florianópolis - Florianópolis (SC), Brazil.ORCID http://orcid.org/0000-0003-0576-4774
Vanda Lúcia CotaFundação Oswaldo Cruz, Sergio Arouca National School of Public Health - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0002-6823-9304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the factors associated with antiretroviral therapy interruption among people living with the human immunodeficiency virus participating in the A Hora é Agora [The Time is Now] project in the municipalities of Campo Grande, Curitiba, and Florianópolis.

methodsThis is a cross-sectional analytical study using data from the Brazilian Medication Logistics Control System, collected between October 2019 and September 2022. Bivariate analyses were performed to assess associations between sex, age group, race/skin color, and level of education, with the outcomes of treatment interruption and the number of times the treatment was interrupted, using the χ2 test with a 5% significance level.

resultsIn Campo Grande, treatment interruption was more frequent among individuals with eight to 11 years of formal education (34.0%). In Curitiba, women (20.4%) showed a higher frequency of treatment interruption, and the age group of 50 years or older had a higher likelihood of treatment interruption (OR: 1.73; 95%CI: 1.12-2.66). In Florianópolis, 31.1% of women experienced treatment interruption, and individuals with up to seven years of formal education had a higher likelihood of treatment interruption (OR: 1.62; 95%CI: 1.15-2.29).

conclusionsThe interruption of antiretroviral therapy was significantly associated with sex, level of education, and age group, with distinct patterns across the analyzed territorial contexts. These findings highlight the need for targeted interventions aimed at vulnerable groups, considering regional differences and local challenges to improve treatment adherence.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV InfectionsAdolescentAdultBrazilCitiesCross-Sectional StudiesEducational StatusFemaleHumansMaleMiddle AgedSocioeconomic FactorsYoung AdultAnti-HIV Agents

Identifiers

PMID40197900
PMCPMC11980824

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.