Evidence map›Paper›PMID 40197883›Full record

ReviewArquivos de gastroenterologia2025

SARCOPENIA AND GASTROINTESTINAL CANCER: NUTRITIONAL APPROACH FOCUSING ON CURCUMIN SUPPLEMENTATION.

Pamela S de Almeida, Katia Barão, Nora M Forones

Registry-linked trialAbstract readReview
In one paragraph

Review in Arquivos de gastroenterologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07003061 (The Effects of Sarcopenia on Neuromuscular Block in Gastrointestinal Cancer Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07003061 completednot on this map

The Effects of Sarcopenia on Neuromuscular Block in Gastrointestinal Cancer Surgery

TypeobservationalSponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalRan2025 to 2026Enrolled100ConditionsGastrointestinal Cancer, Sarcopenia, Neuromuscular BlockadeArmsStandard Anesthesia Management
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pamela S de AlmeidaUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina, Divisão de Gastroenterologia, São Paulo, SP, Brasil.ORCID http://orcid.org/0009-0002-7127-663X
Katia BarãoUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina, Divisão de Gastroenterologia, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-9975-4109
Nora M ForonesUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina, Divisão de Gastroenterologia, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-9414-0343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is a syndrome characterized by decreased strength, quantity and/or quality of skeletal muscle mass. When associated with cancer, it correlates with poorer clinical outcomes. Cancers of the gastrointestinal tract, prevalent globally and in Brazil, are associated with a greater nutritional risk. Early detection and intervention for nutritional risks are critical in this population. Recent studies on turmeric/curcumin have demonstrated beneficial effects in cancer patients. Specifically, curcumin have shown promise in reducing muscle depletion, oxidative stress, and improving strength and fatigue, factors related to sarcopenia. This review aims to elucidate sarcopenia and sarcopenia secondary to cancer, emphasizing nutritional management and the role of curcumin supplementation. Effective cancer management, whether with or without sarcopenia, demands comprehensive public health strategies and multimodal interventions within healthcare institutions. Nutrition is pivotal across the cancer care journey, encompassing screening, guidance, and provision of nutrients that support maintaining or recovering body composition. Curcumin supplementation emerges as a potential adjuvant to the standard cancer treatment and sarcopenia management. Nevertheless, further clinical studies are warranted to substantiate these findings.

background• Sarcopenia is a syndrome characterized by decreased strength, quantity and/or quality of skeletal muscle mass.

background• Sarcopenia when associated with cancer, it correlates with poorer clinical outcomes.

background• Curcumin has shown promise in reducing muscle depletion, oxidative stress, and improving strength and fatigue, factors related to sarcopenia.

background• Curcumin supplementation emerges as a potential adjuvant to the standard cancer treatment and sarcopenia management.

Indexed as

CurcuminDietary SupplementsGastrointestinal NeoplasmsSarcopeniaHumansCurcumin

Identifiers

PMID40197883
PMCPMC12043197

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.