ArticlePediatric pulmonology2025
Respiratory Related Hospitalization in Children With Exposure to Meconium Aspiration or Staining.
Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundWe investigated whether neonates exposed to meconium had a higher risk of respiratory hospitalization in childhood.
methodsWe analyzed a longitudinal cohort of 1,271,563 children with 6,334,857 person-years of follow-up between birth and age 5 years in Quebec, Canada from 2006 to 2022. The exposure was meconium aspiration or meconium staining without aspiration at birth. The outcome was hospitalization for bronchiolitis, asthma, and other allergic conditions up to age 5 years. We estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association between meconium exposure and these outcomes using Cox regression models adjusted for patient characteristics. We additionally examined associations according to gestational age.
resultsA total of 6050 children had meconium aspiration (0.5%) and 131,238 were exposed to meconium without aspiration (10.3%). Compared with no exposure, meconium aspiration was associated with 1.24 times the risk of bronchiolitis (95% CI: 1.09-1.42), 1.43 times the risk of asthma (95% CI: 1.20-1.69), and 1.40 times the risk of other allergy hospitalization (95% CI: 1.11-1.76). Meconium aspiration was associated with these outcomes among children born at term (HR: 1.28, 95% CI: 1.14-1.44) and post-term (HR: 1.56, 95% CI: 1.26-1.94). There was no association for children born preterm. Meconium exposure without aspiration appeared to protect against the outcomes (HR: 0.92, 95% CI: 0.90-0.95), but the association disappeared when we accounted for gestational age.
conclusionMeconium aspiration is associated with a higher risk of hospitalization for respiratory or atopic complications, but meconium exposure without aspiration is not associated with these outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.