Evidence map›Paper›PMID 40197744›Full record

ArticleInflammatory bowel diseases2025

Health Outcomes, Discrimination, and Stigma Among Sexual and Gender Minority People With Inflammatory Bowel Disease.

Kira L Newman, Patricia A Wren, Millie D Long, Peter D R Higgins

Abstract read
In one paragraph

Article in Inflammatory bowel diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Kira L NewmanDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-8279-1111
Patricia A WrenDepartment of Public Health, Wayne State University, Detroit, MI, USA.ORCID 0000-0003-4169-681X
Millie D LongDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0001-5983-2758
Peter D R HigginsDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-1602-4341

Funding

Training Program in Gastrointestinal EpidemiologyT32DK062708 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Peter D.R. Higgins, Elliot Tapper · 2003 to 2026
$3.9M
Measuring Molecular and Mechanical Outcomes of Endoscopic Dilation of Fibrotic StricturesR01DK125687 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Peter D.R. Higgins, Guan Xu · 2020 to 2026
$3.3M
Inhibiting Bcl-2-regulated intestinal fibrosis in models of Crohn’s DiseaseR01DK118154 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HIGGINS, PETER D.R. · 2018 to 2022
$2.3M
Bacterial, Viral, and Host Interactions in the Pathogenesis of Inflammatory Bowel DiseaseF32DK134043 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NEWMAN, KIRA · 2022 to 2022
$81k
American College of Gastroenterology Junior Faculty Career Development AwardCrohn's and Colitis FoundationNational Institute for Diabetes and Digestive and Kidney Diseases of theNIH HHS F32DK134043NIH HHS R01 DK 118154NIH HHS R01 DK125687NIH HHS T32 DK062708
6 · The paper itself

Abstract

backgroundSexual and gender minority (SGM) individuals often experience more discrimination and worse health than non-SGM people. Less is known about SGM individuals with inflammatory bowel disease (IBD). We studied IBD outcomes, discrimination, illness-related stigma, and SGM status in a cross-sectional survey.

methodsIn total, 1586 IBD Partners e-cohort participants self-reported sexual orientation, gender identity, and prior IBD treatment. They completed the Short Crohn's Disease Activity Index or Simple Clinical Colitis Activity Index, the Everyday Discrimination Scale, and the Paradox of Self Stigma (PASS-24) scale. We performed regression analyses controlling for age, race, disease duration, and IBD type.

resultsSGM people were 7.8% (n = 124) of the cohort. SGM participants were younger than non-SGM participants (median age 40 vs. 54 years, P < .001). Among SGM individuals, 67% (n = 74) were in remission based on disease activity scores. Among non-SGM individuals, 74% (n = 936) were in remission (P = .097). Similar proportions of SGM and non-SGM persons reported prior IBD-related hospitalization (40% vs. 37%, P = .426; adjusted odds ratio [aOR] 0.95, 95% confidence interval [CI], 0.62-1.45) and IBD-related surgery (52% vs. 54%, P = .707, aOR 1.25, 95% CI, 0.81-1.94). SGM respondents reported more discrimination (71% vs. 47%, P < .001), and 43% of SGM individuals reported healthcare-related discrimination versus 21% of non-SGM individuals (P < .001). SGM persons also endorsed more internalized stigma (median PASS-24 scores 53 vs. 47, P = .026).

conclusionsSGM individuals with IBD are more likely to experience discrimination, including in healthcare, and illness-related stigma. These may significantly impact the quality of life and should be considered in the care of SGM people with IBD.

Indexed as

Inflammatory Bowel DiseasesSexual and Gender MinoritiesSocial StigmaAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedQuality of LifeYoung AdultCrohn’s diseasehealth disparitiesLGBTQpatient-reported outcomesulcerative colitis

Identifiers

PMID40197744
PMCPMC12455600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.