Evidence map›Paper›PMID 40197659›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2025

Transition readiness assessment in adolescents and young adults with chronic intestinal failure on home parenteral nutrition: A descriptive cross-sectional study.

Aysenur Demirok, Marc A Benninga, Antonella Diamanti, Myriam El Khatib, Anat Guz-Mark, Johannes Hilberath, Cécile Lambe, Lorenzo Norsa, Anna Simona Sasdelli, Alida A Sanchez and 2 more

Abstract readMulticenter Study
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aysenur DemirokPediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2425-979X
Marc A BenningaPediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Antonella DiamantiArtificial Nutrition Unit, Bambino Gesù Pediatric Hospital, Rome, Italy.ORCID http://orcid.org/0000-0002-3926-0729
Myriam El KhatibDepartment of Gastroenterology and Nutrition Support, APHP Beaujon Hospital, Clichy, France.
Anat Guz-MarkInstitute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel and Faculty of Medicine, Tel-Aviv university, Tel-Aviv, Israel.
Johannes HilberathPaediatric Gastroenterology and Hepatology, University Children's Hospital Tübingen, Tübingen, Germany.ORCID http://orcid.org/0009-0005-0055-7452
Cécile LambeDepartment of Pediatric Gastroenterology-Hepatology-Nutrition, Hôpital Necker-Enfants Malades, Université Paris Descartes, Paris, France.
Lorenzo NorsaDepartment of Pediatric Hepatology, Gastroenterology and Transplantation, ASST Papa Giovanni XXIIII, Bergamo, Italy.
Anna Simona SasdelliCentre for Chronic Intestinal Failure, Bologna, Italy.
Alida A SanchezPediatric Gastroenterology, Intestinal Rehabilitation Unit, La Paz University Hospital, Madrid, Spain.
Mireille SerlieLaboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Merit M TabbersPediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsLife expectancy for patients with chronic intestinal failure (CIF) recieving home parenteral nutrition (HPN) has improved over the past decades. Consequently, more children on HPN grow into adulthood. Until now, no assessment of transition readiness of these patients exists. Aim is to assess readiness of adolescents recieving HPN.

methodsThis is an international, prospective, cross-sectional multicenter study in collaboration with members of the Intestinal Failure working group-European Reference Network for Rare Inherited and Congenital (Digestive and Gastrointestinal) Anomalies and the Network of Intestinal Failure and Intestinal Transplant in Europe-European Society for Pediatric Gastroenterology Hepatology and Nutrition conducted between April and November 2023. A validated Transition Readiness Assessment Questionnaire was used to measure patient- and parent-reported transition readiness in adolescents on HPN.

resultsA total of 57 participants aged 16 to 24 years were included across eight countries. Patient-reported outcomes show a lack of readiness for transition among the total cohort with 65% scoring below the threshold. Younger patients (aged 16-18 years), male patients, and those in pediatric settings reported significant lower readiness. Parent-reported scores were higher compared with the patient-reported outcomes, reaching the threshold for transition readiness.

conclusionThe transition readiness of adolescents with CIF receiving HPN presents is proven to be low. This study underscores the necessity for the use of a standardized transition protocol. Emphasizing the importance of successful transition in this vulnerable patient group will enhance the outcomes and independence of adolescents during their transition into the adult healthcare system.

Indexed as

Intestinal FailureParenteral Nutrition, HomeTransition to Adult CareAdolescentChronic DiseaseCross-Sectional StudiesEuropeFemaleHumansMaleParentsPatient Reported Outcome MeasuresProspective StudiesSurveys and QuestionnairesYoung Adultchildrenhome parenteral nutritionintestinal failuretransition

Identifiers

PMID40197659
PMCPMC12230936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.