Evidence map›Paper›PMID 40197389›Full record

ArticleeLife2025

Coordinated regulation of chemotaxis and resistance to copper by CsoR in

Meina He, Yongxin Tao, Kexin Mu, Haoqi Feng, Ying Fan, Tong Liu, Qiaoyun Huang, Yujie Xiao, Wenli Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Regulatory Characterization of Two Cop Systems for Copper Resistance inInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meina HeNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Yongxin TaoNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Kexin MuNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Haoqi FengNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Ying FanNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Tong LiuNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Qiaoyun HuangNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Yujie XiaoNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Wenli ChenNational Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0003-1717-1263

Funding

Fundamental Research Funds for the Central Universities 2662022SKQD002Hubei Provincial Natural Science Foundation of China 2024AFB691National Key Research and Development Program of China 2020YFC1806803National Natural Science Foundation of China 31900054
6 · The paper itself

Abstract

Copper is an essential enzyme cofactor in bacteria, but excess copper is highly toxic. Bacteria can cope with copper stress by increasing copper resistance and initiating chemorepellent response. However, it remains unclear how bacteria coordinate chemotaxis and resistance to copper. By screening proteins that interacted with the chemotaxis kinase CheA, we identified a copper-binding repressor CsoR that interacted with CheA in

Indexed as

Bacterial ProteinsChemotaxisCopperDrug Resistance, BacterialPseudomonas putidaRepressor ProteinsGene Expression Regulation, BacterialMethyl-Accepting Chemotaxis ProteinsPromoter Regions, GeneticProtein BindingBacterial ProteinsCopperMethyl-Accepting Chemotaxis ProteinsRepressor Proteinsbiochemistrychemical biologychemotaxiscopper resistancePseudomonas putida

Identifiers

PMID40197389
PMCPMC11978298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.