SynthesisBMC public health2025
Prevalence of HIV/syphilis co-infection among men who have sex with men in China: a systematic review and meta-analysis.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Secondary Distribution of Dual HIV/Syphilis Self-Testing Among Men Who Have Sex With Men: Pragmatic Randomized Controlled Trial in China.JMIR public health and surveillance · 2025Trial
- Do Sexually Transmitted Infections Coexist? Evidence from Human Immunodeficiency Virus and Syphilis Coinfection in a Tertiary Care Center.Journal of clinical practice and research · 2026Article
- Article
- Trend in the detection rate of syphilis among older adults: time series analysis, Brazil, 2014-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Sexualized Drug Use Linked to Higher HIV Testing Frequency Among Men Who Have Sex with Men in Three Chinese Cities with High HIV Prevalence.Substance use & misuse · 2026Article
- Adherence to on-demand and daily oral pre-exposure prophylaxis for HIV among men who have sex with men in China: a cross-sectional study.BMC infectious diseases · 2025Article
- Infectious Proctitis Mimicking Advanced Rectal Cancer: A Case Report and Update on the Differential Diagnosis of Rectal Ulcerations.Journal of clinical medicine · 2025Article
- Doxycycline prophylaxis for sexually transmitted infections prevention among men who have sex with men in China.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundMen who have sex with men (MSM) are key populations for HIV and syphilis infection, and co-infection with both diseases significantly increases health risks. However, the co-infection of HIV/syphilis among this population in China has not been systematically evaluated. We aimed to conduct a meta-analysis to ascertain the prevalence of HIV/syphilis co-infection among MSM in China.
methodsWe conducted a systematic literature search involving PubMed, Web of Science, CNKI and Wanfang to identify publications reporting HIV/syphilis co-infection among MSM in China. Our search encompassed articles available from the establishment of these databases up to December 31, 2022. Additionally, we examined the references of retrieved articles to identify additional relevant records. The random-effects model fitting Freeman-Tukey double arcsine transformation was employed to estimate the prevalence of HIV/syphilis co-infection and its 95% confidence interval (CI). Heterogeneity was assessed utilizing the I
resultsA total of 46 studies were included, with a total sample size of 50,187 MSM, including1,459 co-infected individuals. The pooled prevalence of HIV/syphilis co-infection among MSM in China was 2.7% (95% CI: 2.2-3.4%), with significant heterogeneity (I
conclusionThe prevalence of HIV/syphilis co-infection among MSM in China was elevated, with certain regional disparities. Notably, the STD clinics attendees and older MSM were more likely to be co-infected. Urgent and targeted measures are needed to enhance interventions for these vulnerable populations to control HIV/syphilis co-infection.
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