Evidence map›Paper›PMID 40197244›Full record

ArticleBMC psychiatry2025

Obsessive-compulsive disorder and temporal lobe porencephaly: a case report.

Gaoju Deng, Yuan Cao, Changjian Qiu

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gaoju DengMental Health Center, West China Hospital of Sichuan University, Sichuan Clinical Medical Research Center for Mental Disorders, No. 37 Guo Xue Alley, Chengdu, Sichuan, China.
Yuan CaoMental Health Center, West China Hospital of Sichuan University, Sichuan Clinical Medical Research Center for Mental Disorders, No. 37 Guo Xue Alley, Chengdu, Sichuan, China.
Changjian QiuMental Health Center, West China Hospital of Sichuan University, Sichuan Clinical Medical Research Center for Mental Disorders, No. 37 Guo Xue Alley, Chengdu, Sichuan, China. qiuchangjian@wchscu.edu.cn.

Funding

1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University 2022HXFH029
6 · The paper itself

Abstract

backgroundThe functional and structural abnormalities of cortico-striato-thalamo-cortex have been reported to be associated with the neurobiological basis of obsessive-compulsive disorder (OCD). OCD can also occur in the striatum damaging after brain infarction, which is called OCD caused by physical diseases. The relationship and mechanism between temporal lobe abnormalities and OCD are still unclear. CASE PRESENTATION: A young male with temporal lobe porencephaly presented with obsessive-compulsive symptoms. The cognition of this OCD participant was not significantly impaired, and his social function was well maintained. After treatment with sertraline, aripiprazole, and fluvoxamine, he was improved but relapsed several times after drug withdrawal. However, the therapeutic effect was sustained upon reinitiation of the medication.

conclusionThis is the first reported case of OCD in an individual with left temporal lobe porencephaly. The possible relationship between obsessive-compulsive symptoms and temporal lobe structural abnormalities needs to be further studied. The maintenance treatment and prognosis of organic obsessive-compulsive disorder also deserve further study.

Indexed as

Obsessive-Compulsive DisorderTemporal LobeAdultAripiprazoleFluvoxamineHumansMagnetic Resonance ImagingMaleSelective Serotonin Reuptake InhibitorsSertralineAripiprazoleFluvoxamineSelective Serotonin Reuptake InhibitorsSertralineObsessive-compulsive disorderPorencephalyTemporal lobe

Identifiers

PMID40197244
PMCPMC11978146

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