Evidence map›Paper›PMID 40197188›Full record

ReviewCurrent neuropharmacology2025

Chinese Multidisciplinary Expert Consensus on Orphan/Anticopper Drugs and Other Non-drug Management of Hepatolenticular Degeneration.

Ren-Min Yang, Tao Feng, Wei Cai, Xu-En Yu, Gang Wang, Yong-Zhu Han, Cun-Xiu Fan, Qiang Xia, Hai-Bo Chen, Xiao-Ping Wang

Abstract readReviewConsensus Statement
In one paragraph

Review in Current neuropharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Can Parkinsonism be a solitary manifestation of Wilson's Disease?Clinical parkinsonism & related disorders · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ren-Min YangDepartment of Neurology, Institute of Neurology, Anhui University of Chinese Medicine, Hefei, China.
Tao FengDepartment of Neurology, Tiantan Hospital Affiliated to Capital Medical University, Beijing, China.
Wei CaiDivision of Surgery Pediatrics, Shanghai Institute of Pediatrics, Shanghai, China.
Xu-En YuDepartment of Neurology, Institute of Neurology, Anhui University of Chinese Medicine, Hefei, China.
Gang WangDepartment of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Ruijin, China.
Yong-Zhu HanDepartment of Neurology, Institute of Neurology, Anhui University of Chinese Medicine, Hefei, China.
Cun-Xiu FanDivision of Basic Medicine, Shanghai International Academician Station (Jiading), Shanghai, China.
Qiang XiaDepartment of Neurology, Liver Transplantation Center, Renji Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hai-Bo ChenDepartment of Neurology, Institute of Geriatric Medicine, Beijing Hospital & National Center of Gerontology, Beijing, China.
Xiao-Ping WangDepartment of Neurology, Liver Transplantation Center, Renji Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

Research Funds of the Center for Xin'An Medicine 2023CXMMTCM002
6 · The paper itself

Abstract

backgroundThis study aims to guide the diagnosis and treatment of hepatolenticular degeneration (also named Wilson's disease, WD) and aid multidisciplinary clinicians in making reasonable and personalized treatment regimens.

objectivesThe authors aim to establish a systemic structure for Chinese Multidisciplinary Expert Consensus on Diagnosis and Treatment of Hepatolenticular Degeneration.

methodsWe collaborated with experts from relevant branches of the Chinese Medical Association and multiple disciplines, along with statistical experts, to formulate this consensus. It is based on advancements in basic and clinical research on Wilson's disease, both domestically and internationally.

resultsIt mainly consists of clinical manifestations, diagnosis, differential diagnosis, management, and prognosis in the context of Multi-Department treatment (MDT) in China.

conclusionThis Chinese consensus incorporates four decades of institutional experience with thousands of Chinese Wilson's disease (WD) inpatients, as well as decades of international inpatient cases from East to West. It is hoped that this consensus will garner broader attention from clinicians worldwide.

Indexed as

Hepatolenticular DegenerationOrphan Drug ProductionChinaConsensusHumansanticopper drugsconsensusguidelinehepatolenticular degeneration.Multidisciplinary expertWilson's disease

Identifiers

PMID40197188
PMCPMC12645139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.