ArticleBMC medical imaging2025
Use of a soft guiding template and laser device improves the success rate of computed tomography-guided bone biopsies and reduces radiation exposure.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPrecision and operator expertise are critical for bone tumour biopsies. In this study, we investigated the impact of combining a soft guiding template with a laser device on the success rate of computed tomography (CT)-guided bone biopsies and the associated radiation dose.
methodsA cohort of 114 patients with bone tumours requiring CT-guided biopsies were assigned to the auxiliary device group, utilising a soft guiding template and a laser device. Another 197 patients (control group) underwent biopsies with conventional guiding templates. The χ2 test compared biopsy success rates and concordance rates between biopsy findings and surgical outcomes. Biopsy success rates for limb bones, limb girdles, and axial bones were also compared. Independent sample t-tests analysed differences in age, volume CT dose index (CTDI
resultsThe biopsy success rate in the auxiliary device group (85.09%) was significantly higher than in the control group (74.62%; P = 0.032). No significant differences were observed for limb girdles (P = 0.40) or axial bones (P = 0.19). However, the biopsy success rate for limb bones was significantly higher in the auxiliary device group (85.51%) than in the control group (70.87%; P = 0.028). The concordance rate between biopsy findings and surgical outcomes did not differ significantly (P = 1.00). CTDI
conclusionThe combination of a soft guiding template and laser device significantly improved the success rate of CT-guided bone biopsies, providing a solid histological foundation for early and accurate diagnosis. Furthermore, these devices reduced the associated radiation dose, lowering radiation-related risks for patients.
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