ArticlemSystems2025
The presence of multiple variants of IncF plasmid alleles in a single genome sequence can hinder accurate replicon sequence typing using
Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Integrative Modular, Network-Based, and Machine Learning Framework for Predicting Accessory Genome Functions and Virulence in Escherichia coli O157:H7.MicrobiologyOpen · 2026Article
- From ecology to evolution: plasmid- and colicin-mediated persistence of antibiotic-resistantmSystems · 2026Article
- Single-cell genomic profiling of antimicrobial resistance inFrontiers in microbiology · 2026Article
- Emergence and characterization of a novel ST627-KL8 carbapenem-resistantFrontiers in microbiology · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
IncF plasmids are mobile genetic elements found in bacteria from the IMPORTANCE: Plasmid sequence type is crucial for describing IncF plasmids due to their capacity to carry important antibiotic and virulence gene cargo and consequently due to their association with disease-causing enterobacterial lineages exhibiting resistance to clinically relevant antibiotics in humans and food-producing animals. As a result, precise reporting of IncF allele variants in IncF plasmids is necessary. Comparison of the FAB formulae generated by the pMLST tool with annotated long-read genome assemblies identified inconsistencies, including examples where multiple IncF allele variants were present on the same plasmid but missing in the FAB formula, or in cases where two IncF plasmids were detected in one bacterial cell, and the pMLST output provided information only about one plasmid. Such inconsistencies may cloud interpretation of IncF plasmid replicon type in specific bacterial lineages or inaccurate assumptions of host strain clonality.
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