Evidence map›Paper›PMID 40197096›Full record

ArticleRadiology2025

Parallel Detection of Multicontrast MRI and Deuterium Metabolic Imaging for Time-efficient Characterization of Neurologic Diseases.

Yanning Liu, Henk M De Feyter, Zachary A Corbin, Robert K Fulbright, Scott McIntyre, Terence W Nixon, Robin A de Graaf

Abstract read
In one paragraph

Article in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yanning LiuMagnetic Resonance Research Center, Department of Biomedical Engineering, Yale University School of Medicine, 300 Cedar St, New Haven, CT 06520-8043.ORCID 0000-0002-7861-9853
Henk M De FeyterMagnetic Resonance Research Center (MRRC), Department of Radiology and Biomedical Imaging, Yale University, New Haven, Conn.ORCID 0000-0001-6111-0316
Zachary A CorbinMagnetic Resonance Research Center (MRRC), Department of Neurology, Yale University, New Haven, Conn.ORCID 0000-0002-9831-8847
Robert K FulbrightMagnetic Resonance Research Center (MRRC), Department of Radiology and Biomedical Imaging, Yale University, New Haven, Conn.ORCID 0000-0002-8204-3594
Scott McIntyreMagnetic Resonance Research Center (MRRC), Department of Radiology and Biomedical Imaging, Yale University, New Haven, Conn.ORCID 0009-0006-3745-8359
Terence W NixonMagnetic Resonance Research Center (MRRC), Department of Radiology and Biomedical Imaging, Yale University, New Haven, Conn.ORCID 0009-0006-7588-0796
Robin A de GraafMagnetic Resonance Research Center, Department of Biomedical Engineering, Yale University School of Medicine, 300 Cedar St, New Haven, CT 06520-8043.ORCID 0000-0002-6570-7010

Funding

Deuterium metabolic imaging (DMI) of neurological diseaseR01EB025840 · NIBIB · YALE UNIVERSITY · PI ROBIN A DE GRAAF, Henk De Feyter · 2019 to 2026
$4.2M
Validation of imaging brain tumor metabolism using deuterated glucoseR01EB033764 · NIBIB · YALE UNIVERSITY · PI ROBIN A DE GRAAF, Henk De Feyter · 2023 to 2026
$2.4M
Time-efficient MRI and deuterium metabolic imaging (DMI) through parallel signal acquisitionR01EB034730 · NIBIB · YALE UNIVERSITY · PI ROBIN A DE GRAAF · 2024 to 2026
$1.4M
Mapping of choline uptake and metabolism in brain tumors with deuterium metabolic imaging (DMI)R03CA267438 · NCI · YALE UNIVERSITY · PI DE FEYTER, HENK · 2023 to 2024
$168k
NCI NIH HHS R03 CA267438NIBIB NIH HHS R01 EB025840NIBIB NIH HHS R01 EB033764NIBIB NIH HHS R01 EB034730
6 · The paper itself

Abstract

Background Deuterium metabolic imaging (DMI) is a novel, MRI-based method to map metabolism noninvasively in vivo and has potential to augment existing clinical MRI with unique metabolic information. However, adding DMI scans to a standard, clinical MRI protocol is challenging due to the relatively long scan time of DMI that can result in decreased patient compliance and increased scanning costs. Purpose To design and evaluate a parallel acquisition strategy, based on the large frequency difference between hydrogen proton (

Indexed as

DeuteriumMagnetic Resonance ImagingNervous System DiseasesAdultBrainContrast MediaFemaleHumansMalePhantoms, ImagingContrast MediaDeuterium

Identifiers

PMID40197096
PMCPMC13051383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.