Evidence map›Paper›PMID 40197035›Full record

ArticlemBio2025

Evolution of PqsE as a

Caleb P Mallery, Kayla A Simanek, Autumn N Pope, Jon E Paczkowski

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. New inhibitors of themSphere · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Caleb P MalleryDepartment of Biomedical Sciences, College of Integrated Health Sciences, University at Albany, Albany, New York, USA.ORCID 0009-0008-1114-513X
Kayla A SimanekDepartment of Biomedical Sciences, College of Integrated Health Sciences, University at Albany, Albany, New York, USA.ORCID 0000-0002-7666-6103
Autumn N PopeDivision of Genetics, New York State Department of Health, Wadsworth Center, Albany, New York, USA.ORCID 0009-0005-4409-009X
Jon E PaczkowskiDepartment of Biomedical Sciences, College of Integrated Health Sciences, University at Albany, Albany, New York, USA.ORCID 0000-0002-8286-3808

Funding

RNA Science and Technology in Health and DiseaseT32GM132066 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Thomas J Begley · 2019 to 2026
$1.8M
Characterization of the mechanisms underpinning quorum sensing progression in Pseudomonas aeruginosaR01GM144361 · NIGMS · WADSWORTH CENTER · PI Jon E Paczkowski · 2022 to 2026
$1.6M
Cystic Fibrosis Foundation PACZKO21G0New York Community Trust P19-000454NIGMS NIH HHS R01 GM144361NIGMS NIH HHS R01GM14436101NIGMS NIH HHS T32 GM132066NIGMS NIH HHS T32GM132066
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

Bacterial ProteinsBurkholderiaEvolution, MolecularPseudomonas aeruginosaRepressor ProteinsTrans-ActivatorsGene Expression Regulation, BacterialProtein BindingQuorum SensingBacterial ProteinsLuxR autoinducer binding proteinsRepressor ProteinsTrans-Activatorsevolutionary biologyproteasomeprotein-protein interactionsquorum sensingtranscriptional regulation

Identifiers

PMID40197035
PMCPMC12077149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.