Evidence map›Paper›PMID 40197034›Full record

ArticleApplied and environmental microbiology2025

Functional disparities of malonyl-ACP decarboxylase between

Mingfeng Yan, Yonghong Yu, Lizhen Luo, Jingtong Su, Jincheng Ma, Zhe Hu, Haihong Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingfeng Yan *Institute of Plant Protection, Jiangxi Academy of Agricultural Sciences, Nanchang, Jiangxi, China.ORCID 0000-0002-1681-5533
Yonghong Yu *Guangdong Food and Drug Vocational College, Guangzhou, Guangdong, China.
Lizhen Luo *Guangdong Provincial Key Laboratory for Developmental Biology and Environmental Adaptation of Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.
Jingtong SuGuangdong Provincial Key Laboratory for Developmental Biology and Environmental Adaptation of Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.
Jincheng MaGuangdong Provincial Key Laboratory for Developmental Biology and Environmental Adaptation of Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.
Zhe HuGuangdong Provincial Key Laboratory for Developmental Biology and Environmental Adaptation of Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.ORCID 0000-0002-6864-2099
Haihong WangGuangdong Provincial Key Laboratory for Developmental Biology and Environmental Adaptation of Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.ORCID 0000-0002-9458-4697

Funding

Characteristic Innovation Project of Colleges and Universities in Guangdong Province 2024KTSCX339Double First-class Discipline Promotion Project 2021B10564001International Science and Technology Program of Guangdong 2022A0505050060Medical Science and Technology Foundation of Guangdong ProvinceNational Natural Science Foundation of China 31972232Natural Science Foundation of Guangdong Province 2021A1515110166Science and Technology Projects in Guangzhou 2024A04J3411
6 · The paper itself

Abstract

IMPORTANCE: Despite the high conservation of the mad gene within the Proteobacteria, the physiological roles of the Mad protein remain largely unclear. Xoo and Xcc are bacteria with very close phylogenetic relationships, both encoding malonyl-ACP decarboxylase (MadB). However, MadB demonstrates substantial physiological function variations between these two species. This study demonstrates that even in closely related bacteria, homologous genes have adopted different evolutionary pathways to adapt to diverse living environments, forming unique gene expression regulation mechanisms. This has led to the biochemical functional divergence of homologous proteins within their respective species, ultimately resulting in distinct physiological functions.

Indexed as

Bacterial ProteinsCarboxy-LyasesXanthomonasXanthomonas campestrisOryzaPlant DiseasesBacterial ProteinsCarboxy-Lyases3-ketoacyl-ACP synthases IIIfatty acid biosynthesismalonyl-ACP decarboxylaseXanthomonas campestris pv. campestrisXanthomonas oryzae pv. oryzae

Identifiers

PMID40197034
PMCPMC12093956

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.