ArticleFrontiers in veterinary science2025
Surface N- or O-linked glycans on bovine spermatozoa play minimal role in evading macrophage mediated phagocytosis.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Bull spermatozoa possess glycocalyx made of carbohydrate moieties attached to proteins and lipids on their membranes that is involved in fertility associated functions including immune evasion in the female reproductive tract. The current study aimed to establish whether the differences in the glycocalyx of spermatozoa provide selective advantage in evading phagocytosis mediated by female macrophages. Based on removal of either N- or O-linked surface glycans from the spermatozoa, their susceptibility to phagocytosis by macrophages was assessed
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