Evidence map›Paper›PMID 40196725›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Successful Treatment of Ustekinumab-Associated Lichenoid Drug Eruption with Upadacitinib: A Case Report.

Manqi Xia, Jing Zhang, Xin Tian, Ziyan Chen, Jingyao Liang, Yumei Liu

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Lichenoid Drug Eruption From Cetirizine Treated With Upadacitinib and Dupilumab.The Journal of clinical and aesthetic dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manqi Xia *Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.
Jing Zhang *Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.
Xin TianDepartment of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.ORCID 0000-0002-3669-4994
Ziyan ChenDepartment of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.
Jingyao LiangDepartment of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.
Yumei LiuDepartment of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, 510095, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ustekinumab is an antibody targeting the common p40 subunit shared by interleukin (IL)-12 and IL-23, demonstrating favorable efficacy in the treatment of psoriasis. Herein, we report the case of a 69-year-old male with psoriasis, managed with ustekinumab, who presented with a new cutaneous eruption. Biopsy findings were consistent with lichenoid drug eruption (LDE). The patient's condition was promptly managed by upadacitinib, a selective Janus kinase (JAK) inhibitor. Physicians need not be overly concerned about this rare adverse reaction. JAK inhibitors may offer new treatment options with an advantage of rapid onset of action for patients experiencing LDE induced by biologic therapies for psoriasis.

Indexed as

lichenoid drug eruptionpsoriasisupadacitinibustekinumab

Identifiers

PMID40196725
PMCPMC11974564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.