Evidence map›Paper›PMID 40196643›Full record

ArticlebioRxiv : the preprint server for biology2025

Dim Light at Night Disrupts the Sleep-Wake Cycle and Exacerbates Seizure Activity in

Yumeng Wang, Ketema N Paul, Gene D Block, Tom Deboer, Christopher S Colwell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yumeng WangDepartment of Psychiatry & Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-5863-0425
Ketema N PaulDepartment of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-0226-9559
Gene D BlockDepartment of Psychiatry & Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA.
Tom DeboerLaboratory for Neurophysiology, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-6402-6248
Christopher S ColwellDepartment of Psychiatry & Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-1059-184X

Funding

UCLA IDDRC: Translational CoreP50HD103557 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peyman Golshani, SUMA JACOB · 2020 to 2026
$9.6M
UCLA Center for Translational Research in Neurodevelopment: UC-TRaNU54HD087101 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOOKHEIMER, SUSAN Y · 2016 to 2020
$6.5M
NICHD NIH HHS P50 HD103557NICHD NIH HHS U54 HD087101
6 · The paper itself

Abstract

Epilepsy is one of the most common comorbidities in individuals with autism spectrum disorders (ASDs). Many patients with epilepsy as well as ASD experience disruptions in their sleep-wake cycle and exhibit daily rhythms in expression of symptoms. Chronic exposure to light at nighttime can disrupt sleep and circadian rhythms. Contactin associated protein-like 2 knockout (

Indexed as

ASDdim light at nightepilepsymiceseizuresex differencesleep-wake rhythm

Identifiers

PMID40196643
PMCPMC11974761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.