In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
16 authors.
Ali NabhaniDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.ORCID 0000-0001-7103-8573 David M DinhDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.ORCID 0000-0003-0936-6642 Eirene Marie Q EdnacotDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.ORCID 0009-0005-5305-3936 Charlotte R K HoffmanDepartment of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.
Daniel S IzrailevskyDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.
Christy M NguyenDepartment of Biological Chemistry, University of California Irvine, Irvine, CA, USA.ORCID 0000-0002-3897-6207 A Maxwell BurroughsNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
L AravindNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0771-253X Benjamin R MorehouseDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.ORCID 0000-0003-3352-5463 Funding
A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Ritimukta Sarangi · 2020 to 2026
$43.3MTRAINING IN SIGNAL TRANSDUCTION &CELL CYCLE REGULATIONT32GM008759 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI AHN, NATALIE G. · 2000 to 2020
$5.9MPredoctoral Training Program in Signaling and Cellular Regulation INCLUDE Down Syndrome SupplementT32GM142607 · NIGMS · UNIVERSITY OF COLORADO · PI Sabrina Leigh Spencer, Tin Tin Su · 2021 to 2026
$3.6MInterdisciplinary Predoctoral Training in Molecular BiophysicsT32GM145437 · NIGMS · UNIVERSITY OF COLORADO · PI JOSEPH J FALKE · 2022 to 2026
$2.5MResearch Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)DP2AT012346 · NCCIH · UNIVERSITY OF COLORADO · PI WHITELEY, AARON THOMAS · 2022 to 2025
$2.4MDefining the mechanisms that drive novel cyclic nucleotide signaling in immune defenseR35GM157311 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Benjamin Robert Morehouse · 2025 to 2026
$760kEvolutionary Analysis and Comparative Genomics of Protein SuperfamiliesZ01LM594244 · NLM · NATIONAL LIBRARY OF MEDICINE · PI IYER, ARAVIND · 2007 to 2008
$524kModernization/operational improvements to basic centrifugation infrastructure of the Shared Instruments Pool in the Department of Biochemistry University of Colorado BoulderR24OD033699 · OD · UNIVERSITY OF COLORADO · PI ERBSE, ANNETTE H · 2022 to 2022
$143kPurchase of an Isothermal Titration CalorimeterS10RR026516 · NCRR · UNIVERSITY OF COLORADO · PI BATEY, ROBERT T · 2010 to 2010
$129kIntramural NIH HHS Z01 LM594244NCCIH NIH HHS DP2 AT012346NCRR NIH HHS S10 RR026516NIGMS NIH HHS P30 GM133894NIGMS NIH HHS R35 GM157311NIGMS NIH HHS T32 GM008759NIGMS NIH HHS T32 GM142607NIGMS NIH HHS T32 GM145437NIH HHS R24 OD033699
6 · The paper itselfAbstract
Bacteria use antiphage systems to combat phages, their ubiquitous competitors, and evolve new defenses through repeated reshuffling of basic functional units into novel reformulations. A common theme is generating a nucleotide-derived second messenger in response to phage that activates an effector protein to halt virion production. Phages respond with counter-defenses that deplete these second messengers, leading to an escalating arms race with the host. Here we discover a novel antiphage system we call Panoptes that detects phage infection by surveying the cytosol for phage proteins that antagonize the nucleotide-derived second messenger pool. Panoptes is a two-gene operon,
Indexed as
Acb2CBASScyclic oligonucleotide based antiphage signaling systemS-2TMβ
Identifiers
PMID40196609
PMCPMC11974786
What OpenQuestion holds
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