Evidence map›Paper›PMID 40196596›Full record

ArticlebioRxiv : the preprint server for biology2025

Biosynthesis and Physiological Significance of Organ-Specific Flavonol Glycosides in Solanaceae.

Doosan Shin, Haohao Zhao, Ethan Tucker, Keun Ho Cho, Dake Liu, Zhixin Wang, Scott Latimer, Gilles Basset, Yu Wang, Yousong Ding and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Doosan ShinHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.ORCID 0000-0003-1384-4192
Haohao ZhaoHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.ORCID 0000-0002-2969-9404
Ethan TuckerPlant Molecular and Cellular Biology Program, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.ORCID 0009-0008-4910-8481
Keun Ho ChoHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.ORCID 0000-0002-8899-4657
Dake LiuDepartment of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, University of Florida, 1345 Center Drive, Gainesville, FL 32610.
Zhixin WangHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.
Scott LatimerHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.
Gilles BassetHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.
Yu WangHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.
Yousong DingDepartment of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, University of Florida, 1345 Center Drive, Gainesville, FL 32610.
Jeongim KimHorticultural Sciences Department, University of Florida, 2550 Hull Rd, Gainesville, FL 32611, USA.ORCID 0000-0002-5618-3948

Funding

NIH Equipment Supplement to R35GM128742R35GM128742 · NIGMS · UNIVERSITY OF FLORIDA · PI Yousong Ding · 2018 to 2026
$3.4M
NIGMS NIH HHS R35 GM128742
6 · The paper itself

Abstract

Flavonols are subclasses of flavonoids, with hundreds of structures identified in plants. This chemical diversity primarily arises from glycosylation, where sugars are selectively added to the flavonol backbone. While flavonol profiles vary across species and organs, the evolutionary forces shaping this chemodiversity and the physiological significance of specific glycosides remain a mystery. Here, we reveal that finely tuned transcriptional regulation and the sugar selectivity of glycosyltransferases drive the formation of distinct organ specific flavonol profiles and a specific flavonol is necessary for male fertility. In Solanaceae pollen, two flavonol glycosides, K2 (kaempferol 3-

Identifiers

PMID40196596
PMCPMC11974848

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.