Evidence map›Paper›PMID 40196532›Full record

ArticlebioRxiv : the preprint server for biology2025

Seth D Veenbaas, Simon Felder, Kevin M Weeks

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

  • Updated by
    2026
5 · Who and what money

Authors and funding

3 authors.

Seth D VeenbaasDepartment of Chemistry, University of North Carolina, Chapel Hill NC 27599-3290.
Simon FelderDepartment of Chemistry, University of North Carolina, Chapel Hill NC 27599-3290.ORCID 0000-0001-5146-5340
Kevin M WeeksDepartment of Chemistry, University of North Carolina, Chapel Hill NC 27599-3290.ORCID 0000-0002-6748-9985

Funding

Discovery and Function of Higher-Order RNA StructureR35GM122532 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Kevin M Weeks · 2017 to 2026
$5.7M
Translational regulation by covalent modification of mRNAR21AG084970 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEEKS, KEVIN M · 2023 to 2023
$426k
NIA NIH HHS R21 AG084970NIGMS NIH HHS R35 GM122532
6 · The paper itself

Abstract

Small molecules that bind specific sites in RNAs hold promise for altering RNA function, manipulating gene expression, and expanding the scope of druggable targets beyond proteins. Identifying binding sites in RNA that can engage ligands with good physicochemical properties remains a significant challenge.

Indexed as

drug-likenessRNA-ligand interactionsRNA pocketsRNA-targeted ligand discovery

Identifiers

PMID40196532
PMCPMC11974927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.