Evidence map›Paper›PMID 40196521›Full record

ArticlebioRxiv : the preprint server for biology2025

Membrane-associated polymerases deliver most of the actin subunits to a lamellipodial network.

Kristen Skruber, David Sept, R Dyche Mullins

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristen SkruberDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, UCSF School of Medicine, San Francisco, CA 94143.ORCID 0000-0003-2054-6652
David SeptDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI.ORCID 0000-0003-3719-2483
R Dyche MullinsDepartment of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, UCSF School of Medicine, San Francisco, CA 94143.ORCID 0000-0002-0871-5479

Funding

Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcellsR35GM118119 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MULLINS, R DYCHE · 2016 to 2025
$4.8M
Dynamic Regulation of the Actin Filament Barbed EndR01GM136822 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEPT, DAVID · 2020 to 2023
$1.2M
NIGMS NIH HHS R01 GM136822NIGMS NIH HHS R35 GM118119
6 · The paper itself

Abstract

Actin filaments are two-stranded protein polymers that form the basic structural unit of the eukaryotic actin cytoskeleton. While filaments assembled from purified actin

Identifiers

PMID40196521
PMCPMC11974892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.