Evidence map›Paper›PMID 40196351›Full record

ArticleFrontiers in medicine2025

The gamma-glutamyl transpeptidase to platelet ratio: a good noninvasive biomarker for predicting for the occurrence and prognosis of patients with hepatitis E virus-related acute liver failure.

Shuai Zhu, Jun Yuan, Feng Ju, Mengmeng Gu, Ze Xiang, Yan Zhang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuai Zhu *Department of Clinical Laboratory, The Fifth People's Hospital of Suzhou/The Affiliated Infectious Diseases Hospital, Suzhou Medical College of Soochow University, Suzhou, China.
Jun Yuan *Department of Laboratory Medicine, The First People's Hospital of Yancheng City, Yancheng, China.
Feng Ju *Department of Laboratory Medicine, The Yangzhou University Jianhu Clinical College, Jianhu, China.
Mengmeng GuDepartment of Clinical Laboratory, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Ze XiangZhejiang University School of Medicine, Hangzhou, China.
Yan ZhangDepartment of Clinical Laboratory, Suzhou Yongding Hospital, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between GPR and hepatitis E has not been reported. This study evaluates the GPR levels in AHE patients and HEV-ALF patients and explores the role of GPR levels in the prognosis of HEV-ALF patients, offering new strategies and methods for the diagnosis and prognosis of HEV-ALF patients. Methods: Serum samples were collected from 206 AHE patients and 217 HEV-ALF patients admitted to the First Affiliated Hospital of Zhejiang University School of Medicine, Suzhou Yongding Hospital, and Nanjing Medical University Affiliated Suzhou Hospital between January 1, 2017, and November 30, 2024. Results: The GPR level in the HEV-ALF group was significantly higher than in the AHE group ( Conclusion: GPR is highly expressed in HEV-ALF patients and is closely related to their prognosis.

Indexed as

acute liver failurediagnosisgamma-glutamyl transpeptidase to platelet ratio (GPR)hepatitis Eprognosis

Identifiers

PMID40196351
PMCPMC11973331

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.