Evidence map›Paper›PMID 40196252›Full record

ArticlemedRxiv : the preprint server for health sciences2025

The missing link: Electronic health record linkage across species offers opportunities for improving One Health.

Kathleen R Mullen, Nadia Saklou, Adam Kiehl, Toan C Ong, G Joseph Strecker, Sabrina Toro, Sue VandeWoude, Ian M Brooks, Tracy Webb, Melissa A Haendel

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kathleen R MullenDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7264, USA.ORCID 0000-0002-5002-8648
Nadia SaklouDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0001-7894-3947
Adam KiehlCollege of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0009-0003-6090-7472
Toan C OngDepartment of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-6787-1407
G Joseph StreckerCollege of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0002-3044-1240
Sabrina ToroDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7264, USA.ORCID 0000-0002-4142-7153
Sue VandeWoudeDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0001-9227-1622
Ian M BrooksDepartment of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0003-2724-936X
Tracy WebbDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, 80523, USA.ORCID 0000-0003-4547-3787
Melissa A HaendelDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7264, USA.ORCID 0000-0001-9114-8737

Funding

Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
Improvements to the LinkML framework to support the Phenomics First open science resourceRM1HG010860 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAENDEL, MELISSA A, MUNGALL, CHRISTOPHER J · 2020 to 2024
$10.3M
Translational Research Workforce Training: Leveraging the Veterinary SpecialistU01TR002953 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI TREPANIER, LAUREN A · 2019 to 2024
$2.6M
The Colorado Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084226 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER, Nanette F. Santoro · 2023 to 2026
$2.5M
NCATS NIH HHS U01 TR002953NCATS NIH HHS UM1 TR004399NHGRI NIH HHS RM1 HG010860NIAMS NIH HHS K12 AR084226
6 · The paper itself

Abstract

Objective -: Significant opportunities for understanding the co-occurrence of conditions across species in coincident households remain untapped. We determined the feasibility of creating a Companion Care Registry (CCR) for analysis of health data from the University of Colorado Health (UCHealth) patients and their companion animals who received veterinary care at the geographically-adjacent Colorado State University Veterinary Teaching Hospital (CSU-VTH). Materials and Methods -: Using a hybrid deterministic and probabilistic record linkage method, non-medical Personally Identifiable Information was securely matched to determine the total number of UCHealth patients within the HIPAA-compliant Health Data Compass Research Data Warehouse (2015-2024) who took a companion animal to the CSU-VTH (2019-2024). Results -: 12,115 matches were identified, indicating 29% of CSU-VTH clients were UCHealth patients. Discussion -: The overlap between CSU-VTH clients and UCHealth patients underscores the potential feasibility and utility of a CCR. Conclusion -: This work provides a mechanism to evaluate environmental and inter-species influences on One Health.

Indexed as

Data GovernanceData LinkageElectronic Health RecordOne HealthPersonally Identifiable Information

Identifiers

PMID40196252
PMCPMC11974984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.