Evidence map›Paper›PMID 40196171›Full record

ArticleRegenerative biomaterials2025

Development and functional evaluation of recombinant type III collagen intrauterine implant gel.

Xinhui Wang, Xiaoju Fan, Yuanxin Zhai, Jie Li, Huilin Sun, Jie Li, Hao Le, Feng Zhang, Li Zhang, Jianhao Wang and 2 more

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Regenerative biomaterials · 2026
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xinhui WangSchool of Pharmacy, Changzhou University, Changzhou 213164, P. R. China.
Xiaoju FanJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Yuanxin ZhaiJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Jie LiJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Huilin SunJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Jie LiJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Hao LeJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Feng ZhangJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Li ZhangSchool of Pharmacy, Changzhou University, Changzhou 213164, P. R. China.
Jianhao WangSchool of Pharmacy, Changzhou University, Changzhou 213164, P. R. China.
Yun ChuJiangsu Trautec Medical Technology Co, Ltd, Changzhou 213200, P. R. China.
Pengfei CuiSchool of Pharmacy, Changzhou University, Changzhou 213164, P. R. China.ORCID https://orcid.org/0000-0001-7925-0202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine adhesion (IUA) is a prevalent complication arising from uterine surgery, significantly impacting women's fertility and overall quality of life. The conventional clinical approach involves hysteroscopic separation of uterine adhesions, though this method poses operational challenges and carries risks of postoperative re-adhesion. Alternatively, the intraoperative placement of intrauterine devices or support balloons can act as a physical barrier to prevent adhesion formation. However, its effectiveness is limited and it may result in secondary damage to the endothelial tissue. To tackle these challenges, we have engineered a temperature-responsive hydrogel incorporating Pluronic HP407/HP188 pharmaceutical excipients and recombinant type III collagen (rCol III) as a bioactive element. Upon

Indexed as

anti-fibrosisendometrial regenerationintrauterine adhesionrCol IIItemperature-responsive hydrogels

Identifiers

PMID40196171
PMCPMC11975284

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.