Evidence map›Paper›PMID 40196106›Full record

ArticleCureus2025

Genetic Insights Into Early-Onset Type 2 Diabetes Mellitus: The Role of SOST and LRP5 Genotypic Variants in Young Indians.

Jiya Singh, Praveen K Singh, Rahul Amoli, Ravi Kant, Anissa A Mirza, Manisha Naithani, Sarama Saha

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiya SinghBiochemistry, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Praveen K SinghBiochemistry, Maharishi Markandeshwar Medical College & Hospital, Solan, IND.
Rahul AmoliBiochemistry, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Ravi KantGeneral Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Anissa A MirzaBiochemistry, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Manisha NaithaniBiochemistry, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Sarama SahaBiochemistry, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Type 2 diabetes mellitus (T2DM) presents a significant global health challenge, with increasing prevalence rates. The pathogenesis of early-onset T2DM is complex, with the Wnt signaling pathway playing a crucial role in islet cell development. Purpose This study was designed to explore the association of sclerostin (

Indexed as

early-onset diabetesgene polymorphismlow-density lipoprotein receptor-related protein-5 (lrp5)sclerostin (sost)type 2 diabetes mellitus (t2dm)wnt signaling pathway

Identifiers

PMID40196106
PMCPMC11973410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.