Evidence map›Paper›PMID 40196085›Full record

ArticleCureus2025

A Survey on the Use of Cannabidiol (CBD) Isolate, Its Perceived Benefits, and Associated Side Effects Among Subjects With Chronic Pain.

Austin Huang, Laurence Stolzenberg, Mohammad Usman, Muhammad Awan, Paul Bruner, Gordon MacGregor

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Austin HuangNeurology, Alabama College of Osteopathic Medicine, Dothan, USA.
Laurence StolzenbergRadiology, Firelands Regional Medical Center, Sandusky, USA.
Mohammad UsmanPsychiatry, Alabama College of Osteopathic Medicine, Dothan, USA.
Muhammad AwanClinical Sciences, Alabama College of Osteopathic Medicine, Dothan, USA.
Paul BrunerFamily Medicine, Northern Ohio Medical Specialists (NOMS) Healthcare, Sandusky, USA.
Gordon MacGregorPharmacology, Alabama College of Osteopathic Medicine, Dothan, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic pain is a pervasive health issue in the United States, affecting up to 50 million adults and contributing to a substantial economic burden. The worsening opioid crisis has increased the need for nonopiate, nonaddictive alternatives to pain management. Cannabidiol (CBD) has recently garnered attention for its potential analgesic and anti-inflammatory properties without addictive or dependence potential. However, there is limited research regarding the efficacy and safety of CBD in the treatment of chronic pain. This study aimed to explore the use of CBD isolate in adults suffering from chronic pain.

methodsWe decided to investigate its perceived effectiveness, dosage, frequency of use, and reported side effects through a publicly available, completely anonymous Qualtrics survey. This survey was posted online and in multiple medical clinics.

resultsThe key findings of our anonymous online survey are that the use of cannabinoids is positively associated with decreased chronic pain, even at low dosages (<100 mg). In addition, though some mild side effects are noted, the majority of patients self-report no side effects, and there are no noted severe side effects.

conclusionThese findings suggest that CBD may serve as a promising alternative to conventional pain management strategies. However, the results warrant further investigation and research into the efficacy and safety of CBD for chronic pain. We believe these data point the way for new and continued avenues of research that can better optimize treatment regimens and help patients with chronic pain.

Indexed as

cannabis usecbd productschronic pain managementmarijuana useopioid medication

Identifiers

PMID40196085
PMCPMC11973414

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.