Evidence map›Paper›PMID 40195966›Full record

ReviewDementia & neuropsychologia2025

Advancements in the treatment of Alzheimer's disease: a comprehensive review.

Srushti Rajanna, Prajwal Pradeep Gundale, Apoorva Dev Mahadevaiah

Abstract readReview
In one paragraph

Review in Dementia & neuropsychologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The Effect of CuACS chemical neuroscience · 2026
    Article
  3. Review
  4. Human IL-34 Deficiency Primes Microglia Toward Alzheimer's Disease-Associated States.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Srushti RajannaEast West College of Pharmacy, Department of Pharmacy Practice, Bengaluru, Karnataka, India.ORCID https://orcid.org/0009-0003-2005-3433
Prajwal Pradeep GundaleEast West College of Pharmacy, Department of Pharmacy Practice, Bengaluru, Karnataka, India.ORCID https://orcid.org/0009-0004-3634-7839
Apoorva Dev MahadevaiahEast West College of Pharmacy, Department of Pharmacy Practice, Bengaluru, Karnataka, India.ORCID https://orcid.org/0000-0002-5094-4443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and behavioral changes. Despite being the most common cause of dementia, effective treatments have been elusive. However, recent years have witnessed significant advancements in understanding and treating Alzheimer's. Key to these advancements is the shift toward targeted therapies tailored to individual genetic and biomarker profiles, promising more effective outcomes while minimizing side effects. The integration of advanced neuroimaging techniques has revolutionized early diagnosis and disease monitoring, enabling proactive intervention strategies that may alter disease trajectories. This review provides an overview of these advancements, focusing on disease-modifying therapies, symptomatic treatments, combination therapies, lifestyle interventions, biomarker development, innovative drug delivery systems, immunotherapy, gene therapy, and neuroprotective agents.

Indexed as

Alzheimer DiseaseBiomarkersGenetic TherapyNeuroimagingNeuroprotective Agents

Identifiers

PMID40195966
PMCPMC11975295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.