ReviewDementia & neuropsychologia2025
The conundrum of the connection between severe psychiatric disorders and dementia.
Review in Dementia & neuropsychologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Clinical dietitian-led nutrition counseling and exercise to reduce cardiovascular risk in adults living with a BMI above 27 and severe mental illness: the NORMI-Heart trial protocol.Frontiers in nutrition · 2026Article
- Interplay between Peripheral and Central Nervous System Myeloid Cells during Aging: Impact for Lade-Life Depression and Alzheimer's Disease.Neuroimmunomodulation · 2026Review
- Immunopsychiatry of late life depression: role of ageing-related immune/inflammatory processes in the development and progression of depression.Acta neuropsychiatrica · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychiatric disorders have been recognized as important risk factors for neurodegenerative diseases, especially dementia. The strength of association varies among different psychiatric conditions, being more pronounced in severe mental illnesses, i.e., schizophrenia and bipolar disorder. Multiple mechanisms seem to underlie this association, such as high prevalence of cardiovascular and other physical morbidities, poor lifestyle choices, and accelerated aging, including 'inflammaging'. They all represent opportunities for intervention, but it is still unclear whether current therapeutic approaches for psychiatric disorders can prevent the development of dementia. Other knowledge gaps include whether the risk of dementia applies to all patients with a certain condition, or if subgroups of patients are more vulnerable than others, whether different types of dementia are linked to specific psychiatric disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.