Evidence map›Paper›PMID 40195874›Full record

ArticleLeukemia & lymphoma2025

Hematology-oncology provider perspectives regarding lymphoma treatment and cardioprotective strategies in patients with lymphoma at high risk for heart failure.

Emily Anderson, Yun Choi, Rachel J Buchsbaum, Andreas Klein, Bonnie Ky, Daniel Landsburg, Urshila Durani, Kathryn J Ruddy, Anthony F Yu, Darryl Leong and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia & lymphoma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Emily AndersonDepartment of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.
Yun ChoiDivision of Hematology-Oncology, Tufts Medical Center, Boston, MA, USA.
Rachel J BuchsbaumDivision of Hematology-Oncology, Tufts Medical Center, Boston, MA, USA.
Andreas KleinDivision of Hematology-Oncology, Tufts Medical Center, Boston, MA, USA.
Bonnie KyDivision of Cardiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Daniel LandsburgDivision of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Urshila DuraniDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Kathryn J RuddyDivision of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
Anthony F YuDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Darryl LeongDepartment of Medicine and the Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada.
Aarti AsnaniDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Tomas G NeilanDivision of Cardiology, Massachusetts General Hospital, Boston, MA, USA.
Sarju GanatraDivision of Cardiology, Lahey Clinic, Burlington, MA, USA.ORCID 0000-0003-0296-6864
Michelle BloomDivision of Cardiology, NYU Langone Health, New York, NY, USA.
Ana BaracDivision of Cardiology, Inova Schar Heart and Vascular, Fairfax, VA, USA.
Eric H YangDivision of Cardiology, UCLA Cardio-Oncology Program, University of California, Los Angeles Medical Center, Los Angeles, CA, USA.
Anita DeswalDepartment of Cardiology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Richard K ChengDivision of Cardiology, University of Washington Medical Center, Seattle, WA, USA.
Matthias WeissThedacare Regional Cancer Center, Appleton, WI, USA.
Andrew M EvensRutgers Cancer Institute, New Brunswick, NJ, USA.
Brad KahlDivision of Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Jonathan W FriedbergWilmot Cancer Institute, University of Rochester, Rochester, NY, USA.
Susan K ParsonsDivision of Hematology-Oncology, Tufts Medical Center, Boston, MA, USA.
Jenica N UpshawTufts Medical Center, Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Prevention of Anthracycline Chemotherapy CardiotoxicityK08HL146959 · NHLBI · TUFTS MEDICAL CENTER · PI UPSHAW, JENICA · 2020 to 2024
$885k
MENTORING IN PATIENT-ORIENTED RESEARCH IN DEEP PHENOTYPING IN CARDIO-ONCOLOGYK24HL167127 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Bonnie Ky · 2023 to 2026
$496k
NCI NIH HHS P30 CA008748NHLBI NIH HHS K08 HL146959NHLBI NIH HHS K24 HL167127
6 · The paper itself

Abstract

The optimal treatment of patients with diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma (HL) with preexisting cardiomyopathy is uncertain. An anonymous, electronic survey was distributed by e-mail to three US lymphoma cooperative groups, two community hospitals, and twelve academic medical systems, and distributed at one international lymphoma meeting. Fifty hematology-oncology providers caring for patients with lymphoma were included. In response to a vignette of a 67-yo with Stage III DLBCL with LVEF of 40-45%, 15 (30%) would use non-anthracycline regimens, 13 (26%) R-CHOP with liposomal doxorubicin instead of doxorubicin, 11 (22%) R-CHOP without modification and 6 (12%) R-CHOP with a continuous doxorubicin infusion. In a second vignette of a patient with HL in remission after frontline treatment with doxorubicin cumulative dose 300 mg/m

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsHeart FailureHodgkin DiseaseLymphomaLymphoma, Large B-Cell, DiffusePractice Patterns, Physicians'CyclophosphamideDoxorubicinHematologyHumansMaleMedical OncologyPrednisoneSurveys and QuestionnairesVincristineCyclophosphamideDoxorubicinPrednisoneVincristineAnthracyclinecancercancer survivorshipcardiomyopathycardioprotectionheart failure

Identifiers

PMID40195874
PMCPMC12310377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.