Evidence map›Paper›PMID 40195832›Full record

ReviewJournal of microbiology (Seoul, Korea)2025

Advancements in the production of value-added products via methane biotransformation by methanotrophs: Current status and future perspectives.

Ok Kyung Lee, Jong Seok Lee, Yoonyong Yang, Moonsuk Hur, Kyung Jin Lee, Eun Yeol Lee

Abstract readReview
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Advancing microbial engineering through synthetic biology.Journal of microbiology (Seoul, Korea) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ok Kyung LeeDepartment of Chemical Engineering (BK21 FOUR Integrated Engineering), Kyung Hee University, Gyeonggi-do 446-701, Republic of Korea.
Jong Seok LeeNational Institute of Biological Resources(NIBR), Incheon 22689, Republic of Korea.
Yoonyong YangNational Institute of Biological Resources(NIBR), Incheon 22689, Republic of Korea.
Moonsuk HurNational Institute of Biological Resources(NIBR), Incheon 22689, Republic of Korea.
Kyung Jin LeeNational Institute of Biological Resources(NIBR), Incheon 22689, Republic of Korea.
Eun Yeol LeeDepartment of Chemical Engineering (BK21 FOUR Integrated Engineering), Kyung Hee University, Gyeonggi-do 446-701, Republic of Korea.

Funding

Ministry of EnvironmentNational Institute of Biological Resources NIBR202423203
6 · The paper itself

Abstract

Methane gas is recognized as a promising carbon substrate for the biosynthesis of value-added products due to its abundance and low price. Methanotrophs utilized methane as their sole source of carbon and energy, thus they can serve as efficient biocatalysts for methane bioconversion. Methanotrophs-catalyzed microbial bioconversion offer numerous advantages, compared to chemical processes. Current indirect chemical conversions of methane suffer from their energy-intensive processes and high capital expenditure. Methanotrophs can be cell factories capable of synthesizing various value-added products from methane such as methanol, organic acids, ectoine, polyhydroxyalkanoates, etc. However, the large-scale commercial implementation using methanotrophs remains a formidable challenge, primarily due to limitations in gas-liquid mass transfer and low metabolic capacity. This review explores recent advancements in methanotroph research, providing insights into their potential for enabling methane bioconversion.

Indexed as

MethaneBiocatalysisBiotransformationMethanolMethaneMethanolbioconversionmethanemethanotrophsvalue-added products

Identifiers

PMID40195832
PMCPMC13577109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.