Evidence map›Paper›PMID 40195670›Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

RNA-binding proteins regulate osteoarthritis via RNA metabolism regulation.

Jingyue Su, Siyu Chen, Shengwu Yang, Zhenhan Deng

Abstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingyue SuGraduate School, Guangxi University of Chinese Medicine, Nanning, 530001. 18185038937@163.com.
Siyu ChenGraduate School, Guangxi University of Chinese Medicine, Nanning, 530001.
Shengwu YangDepartment of Orthopaedic Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou Zhejiang 325000.
Zhenhan DengGraduate School, Guangxi University of Chinese Medicine, Nanning, 530001. dengzhenhan@wmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a common chronic degenerative disease of the skeletal system and muscular system, and its pathogenesis remains unclear, leading to a lack of effective therapeutic strategies. Ribonucleic acid binding proteins (RBP), as key regulators of post-transcriptional processes, can specifically bind to targeted ribonucleic acids (RNA) and modulate their function and fate. By regulating various aspects of RNA metabolism, including transcription, splicing, modification, stabilization, and translation, RBPs influence the onset and progression of OA. Exploring the regulatory mechanisms of RBPs under physiological and pathological conditions, elucidating the role of RBPs in the occurrence and development of OA, and discussing current challenges and future directions in RBPs research, hold significant importance for the treatment of OA by targeting RBPs.

Indexed as

OsteoarthritisRNARNA-Binding ProteinsAnimalsHumansRNARNA-Binding Proteinsgene expression regulationosteoarthritisRNA-binding proteinsRNA metabolism

Identifiers

PMID40195670
PMCPMC11975523

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.