Evidence map›Paper›PMID 40195359›Full record

ReviewCell death discovery2025

DRP1, fission and apoptosis.

Nan Wang, Xinwai Wang, Beiwu Lan, Yufei Gao, Yuanyuan Cai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell death discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. DRP1 depletion protects NK cells from hypoxia-induced dysfunction.Redox report : communications in free radical research · 2026
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  20. Mitochondrial regulation of cellular senescence heterogeneity.Frontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nan WangThe Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.ORCID http://orcid.org/0000-0002-5920-9314
Xinwai WangThe Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Beiwu LanThe Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Yufei GaoThe Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China. gaoyf@jlu.edu.cn.ORCID http://orcid.org/0000-0003-1200-559X
Yuanyuan CaiThe First Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China. caiyuanyuan1988@jlu.edu.cn.

Funding

Department of Finance of Jilin Province (Jilin Provincial Department of Finance) 2023SCZ60Department of Science and Technology of Jilin Province (Jilin Province Science and Technology Department) 20200601002JCDepartment of Science and Technology of Jilin Province (Jilin Province Science and Technology Department) 20240304035SFDepartment of Science and Technology of Jilin Province (Jilin Province Science and Technology Department) YDZJ202301ZYTS035National Science Foundation of China | Young Scientists Fund 32300594
6 · The paper itself

Abstract

Mitochondrial fission is a critical physiological process in eukaryotic cells, participating in various vital activities such as mitosis, mitochondria quality control, and mitophagy. Recent studies have revealed a tight connection between mitochondrial fission and the mitochondrial metabolism, as well as apoptosis, which involves multiple cellular events and interactions between organelles. As a pivotal molecule in the process of mitochondrial fission, the function of DRP1 is regulated at multiple levels, including transcription, post-translational modifications. This review follows the guidelines for Human Gene Nomenclature and will focus on DRP1, discussing its activity regulation, its role in mitochondrial fission, and the relationship between mitochondrial fission and apoptosis.

Identifiers

PMID40195359
PMCPMC11977278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.