Evidence map›Paper›PMID 40195259›Full record

ArticleOdontology2026

Pan-immune-inflammatory value and systemic immune-inflammatory index in relation to osteoradionecrosis of the jaws: a single institutional experience over 15 years.

Chen-Xi Li, Zhong-Cheng Gong, Sakendeke Jumatai, Chang Fang, Parekejiang Pataer, Hua-Rong Zhao

Abstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chen-Xi LiDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China. lichenxiuke@gmail.com.ORCID http://orcid.org/0000-0003-1443-4769
Zhong-Cheng GongDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China. gzc740904@xjmu.edu.cn.ORCID http://orcid.org/0000-0002-1871-1500
Sakendeke JumataiDepartment of Oral and Maxillofacial Radiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, China.
Chang FangDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China.
Parekejiang PataerDepartment of Oral and Maxillofacial Oncology & Surgery, School / Hospital of Stomatology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China.
Hua-Rong ZhaoDivision of Radiation Oncology, Cancer Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, China.

Funding

National Natural Science Foundation of China 82360481Scientific Research Innovation Project - Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration 2022kqhm008Tianshan Meritocrat Leading Talents in Medicine and Healthcare TSYC202301A001
6 · The paper itself

Abstract

Osteoradionecrosis of the jaws (ORNJ) is a pernicious complication of radiation therapy that significantly affects the quality of life of patients with head and neck cancer. The present study aims to investigate the risk factors for the clinical prognosis of ORNJ in the same scenario. A cross-sectional study was designed and implemented in a tertiary teaching hospital from January 2005 to December 2020. A total of 106 patients were divided into normal wound-healing group (n = 79) and delayed wound-healing group (n = 27) according to two different prognosis. The risk factors associated with the prognosis in patients with ORNJ were comparatively analyzed via performing one-way and multifactorial logistic analyses. The majority of the study cohort (n = 59, 55.7%) was found to be characterized with Glanzmann and Gratz grade 2 and followed up for a median of 38.6 months. Diabetes mellitus (p = 0.045), Charlson comorbidity index (p = 0.042), American Society of Anesthesiologists score (p < 0.001), primary tumor site (p = 0.012), T stage (p = 0.008), ORNJ grade at initial diagnosis (p < 0.001), pan-immune-inflammatory value and systemic immune-inflammatory index at initial radiotherapy (p = 0.01 and p < 0.001 respectively) were detected as risk factors associated with poor prognosis in patients with ORNJ. We conclude that there are abundant risk factors for poor prognosis in these patients, and it is important to be evaluated before irradiation so that suitable post-radiated treatments can be given.

Indexed as

Head and Neck NeoplasmsJaw DiseasesOsteoradionecrosisAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrognosisRisk FactorsClinical prognosisJawOsteoradionecrosisPan-immune-inflammatory valueSystemic immune-inflammatory index

Identifiers

PMID40195259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.