Evidence map›Paper›PMID 40195198›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

A COSMIN systematic review of generic patient-reported outcome measures in Switzerland.

Thanh Elsener, Matthew Kerry, Nikola Biller-Andorno

Abstract readSystematic Review
In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thanh ElsenerInstitute of Public Health, ZHAW Zurich University of Applied Sciences, Katharina-Sulzer-Platz 9, Winterthur, 8400, Zurich, Switzerland. else@zhaw.ch.
Matthew KerryInstitute of Public Health, ZHAW Zurich University of Applied Sciences, Katharina-Sulzer-Platz 9, Winterthur, 8400, Zurich, Switzerland. kerr@zhaw.ch.ORCID http://orcid.org/0000-0002-1339-899X
Nikola Biller-AndornoInstitute of Biomedical Ethics and History of Medicine, University of Zürich, Winterthurerstrasse 30, 8006, Zürich, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 212698
6 · The paper itself

Abstract

purposeTo conduct a systematic review of the quality of generic patient-reported outcome measures (PROMs) for clinical or population research or practice using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology, and to derive recommendations for usage of generic PROMs within Switzerland.

methodsWe searched six databases (PubMed, CINAHL, Web of Science, PsycINFO, EMBASE, Cochrane) and grey literature in Switzerland to identify studies reporting on the development or validation of any generic PROMs used in Switzerland. Methodological quality of each study was assessed with COSMIN's Risk of Bias Checklist. Measurement property evidence (content validity and psychometrics) was further evaluated according to COSMIN's criteria for good measurement properties. Overall evidence was synthesized according to COSMIN's modified GRADE approach to generate recommendations for future use or disuse of generic PROMs within Switzerland.

resultsData from k = 49 studies reporting on five PROMs (EQ-5D, SF-36, PROMIS-29, WHOQOL-BREF, WORQ) were included. Among these, the SF-36 can be recommended for use. The PROMIS-29, WHOQOL-BREF, and WORQ have the potential to be recommended for use, but require further validation. The EQ-5D is not recommendable for future use.

conclusionWith a limited number of content validity studies, WHOQOL-BREF showed sufficiency with moderate quality, while other PROMs showed mixed quality ranging from very low to moderate. Synthesizing all measurement property evidence, SF-36 was identified as recommendable. PROMIS-29, WHOQOL-BREF, and WORQ were identified as potentially recommendable pending further validation evidence. The EQ-5D was identified as unrecommendable for future use within Switzerland.

Indexed as

Patient Reported Outcome MeasuresQuality of LifeHumansPsychometricsReproducibility of ResultsSurveys and QuestionnairesSwitzerlandContent validityCOSMINGeneric PROMHealth-related Quality of lifeMeasurement propertiesSwitzerlandSystematic reviews

Identifiers

PMID40195198
PMCPMC12182498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.