ArticleSocial psychiatry and psychiatric epidemiology2025
The prospective association of adolescent loneliness and low resilience with anxiety and depression in young adulthood: The HUNT study.
Article in Social psychiatry and psychiatric epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Exploring the Power of Peer-Related Social Factors in Mediating the Effects of Pain on Loneliness and Stress in Adolescents.European journal of pain (London, England) · 2026Article
- How resilience and age shape the link between negative life events and suicidal ideation in clinically depressed adolescents: a multicenter study.BMC psychiatry · 2026Article
- Effects of Loneliness and Subjective Well-Being on Depression in Female Adolescents: A Longitudinal Moderated Mediation Model of the Parental Relationship.Psychiatry investigation · 2026Article
- How digital mindfulness training promotes meaning in life among social workers: a parallel mediation analysis and latent profile analysis.Frontiers in psychiatry · 2025Article
- Exploring the Relationship Between Perceived Social Support and Psychological Resilience Among Chinese Adolescents in Post-Pandemic Online Learning Contexts: The Mediating Role of Loneliness.Inquiry : a journal of medical care organization, provision and financingArticle
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Abstract
backgroundLoneliness is a recognized risk factor for anxiety and depression, yet research on its interaction with low resilience remains sparse, particularly across the adolescent-to-adult transition. This study investigates how adolescent loneliness, both independently and in interaction with low resilience, influences anxiety and depression in young adulthood.
methodsThis study utilized longitudinal data from The Trøndelag Health Study (HUNT) to track adolescents (13-19 years) from Young-HUNT3 (2006-08) through to HUNT4 (2017-19). Loneliness was assessed via a single-item measure, while resilience was estimated using the Resilience Scale for Adolescents. Anxiety and depression outcomes at the 11-year follow-up were measured using the Hospital Anxiety and Depression Scale. Multivariable logistic regression analyses were done to analyze the associations. Moreover, interaction effects were evaluated using relative excess risk due to interaction (RERI).
resultsLoneliness during adolescence independently predicted anxiety and depression in young adulthood. Adolescents experiencing both loneliness and low resilience showed notably higher risks compared to other groups (highly resilient adolescents without loneliness [reference], highly resilient adolescents with loneliness, and adolescents with low resilience and low loneliness). The combined effect of loneliness and low resilience exhibited a synergistic interaction on the additive scale, although it was not statistically significant (RERI 0.13, 95% CI -2.39-2.65).
conclusionAdolescent loneliness and low resilience independently predict anxiety and depression in young adulthood. The interaction between loneliness and low resilience further heightens these risks. This underscores the importance of early interventions that focus on resilience-building during adolescence and reducing the impacts of loneliness on mental health.
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