Observational studyAnnals of transplantation2025
Long-Term Outcomes of Left Renal Vein Ligation in Living Donor Liver Transplantation: A 20-Year Study.
Observational study in Annals of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Renoportal anastomosis in pediatric living donor liver transplantation: a case report.Clinical transplantation and research · 2026Article
- Long-Term Renal Outcomes Following Left Renal Vein Ligation Versus Direct Splenorenal Shunt Ligation in Living Donor Liver Transplantation: A 10-Year Single-Center Study.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Persistence of large spontaneous splenorenal shunt (SSRS) can result in graft failure in adult living donor liver transplantation (LDLT) due to portal flow steal; thus, it is necessary to block SSRS to ensure sufficient portal blood flow. MATERIAL AND METHODS We performed a retrospective 20-year observational follow-up study subsequent to a prior prospective study to evaluate the long-term outcomes following ligation of the proximal left renal vein (LRV). Between October 2001 and January 2005, 44 liver cirrhosis patients underwent LDLT with LRV ligation. These patients were followed up until April 2024 or patient death. RESULTS Portal flow was significantly increased after LRV ligation. Renal function recovered uneventfully after LDLT in 40 patients. Eighteen patients died due to cancer recurrence (n=6), pneumonia (n=3), and other causes (n=9), thus 1-, 5-, 10-, and 20-year overall patient survival rates were 95.5%, 86.4%, 81.8%, and 59.1%, respectively. Solitary atrophy of the left kidney was not observed. SSRS was completely resolved in 20 patients, but the other 20 patients showed persistently identifiable SSRS of variable extents to date or at patient death. The LRV was reopened to make large SSRS in another 4 patients, in which retrograde transvenous obliteration was performed in 2 for variceal bleeding control and in another 2 for portal flow augmentation. CONCLUSIONS This study demonstrated that LRV ligation is a safe and effective method to control SSRS. Currently, direct ligation of the SSRS is preferred, but LRV ligation still can be a good therapeutic option when direct access to SSRS is not feasible.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.