Evidence map›Paper›PMID 40195063›Full record

ArticleGut microbes2025

3'-Sialyllactose and

Mingzhi Yang, Zipeng Jiang, Lutong Zhou, Nana Chen, Huan He, Wentao Li, Zhixin Yu, Siming Jiao, Deguang Song, Yizhen Wang and 2 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Effects and mechanism ofWorld journal of gastroenterology · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Ameliorative effects and mechanism ofFrontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mingzhi YangCollege of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID 0009-0000-1370-0864
Zipeng JiangCollege of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID 0009-0002-9140-7799
Lutong ZhouCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Nana ChenCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Huan HeCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Wentao LiCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Zhixin YuCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Siming JiaoInstitute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
Deguang SongDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, USA.
Yizhen WangCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Mingliang JinCollege of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID 0000-0001-6358-5307
Zeqing LuCollege of Animal Sciences, Zhejiang University, Hangzhou, China.ORCID 0000-0002-0720-4693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) poses significant threats to human health and quality of life worldwide, as it is a chronic inflammatory bowel disease. 3'-sialyllactose (3'-SL) is a key functional component of milk oligosaccharides. This study systematically evaluates the prebiotic effects of 3'-SL and its therapeutic potential in combination with

Indexed as

Bifidobacterium longum subspecies infantisColitis, UlcerativeFatty Acids, VolatileGastrointestinal MicrobiomeOligosaccharidesAnimalsBacteriaColonDisease Models, AnimalHumansIntestinal MucosaMaleMiceMice, Inbred C57BLPrebioticsSynbiotics3'-sialyllactoseFatty Acids, VolatileOligosaccharidesPrebiotics3'-SialyllactoseBifidobacterium infantiscross-feedinggut microbiotaintestinal barriershort-chain fatty acidsynbiotic therapyulcerative colitis

Identifiers

PMID40195063
PMCPMC11988227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.