Evidence map›Paper›PMID 40194963›Full record

ArticleJournal of the American Heart Association2025

Impact of Social Determinants of Health on Outcomes of Nontraumatic Subarachnoid Hemorrhage.

Daniela Renedo, Cyprien A Rivier, Andrew Koo, Santiago Clocchiatti-Tuozzo, Shufan Huo, Nanthiya Sujijantarat, Victor M Torres-Lopez, Ryan M Hebert, Lee Schwamm, Adam de Havenon and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniela RenedoDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0003-4120-6649
Cyprien A RivierDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0002-1148-1829
Andrew KooDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.ORCID 0000-0002-2854-649X
Santiago Clocchiatti-TuozzoDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0001-5377-434X
Shufan HuoDepartment of Neurology Yale School of Medicine New Haven CT USA.
Nanthiya SujijantaratDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.ORCID 0000-0002-5857-5718
Victor M Torres-LopezDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0002-2107-2922
Ryan M HebertDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.
Lee SchwammDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.ORCID 0000-0003-0592-9145
Adam de HavenonDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0001-8178-8597
Murat GunelDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.
Charles C MatoukDepartment of Neurosurgery Yale School of Medicine New Haven CT USA.ORCID 0000-0003-3234-9541
Guido J FalconeDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0002-6407-0302
Kevin N ShethDepartment of Neurology Yale School of Medicine New Haven CT USA.ORCID 0000-0003-2003-5473

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Lauren Ferrante · 2002 to 2026
$37.9M
Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)U01NS106513 · NINDS · YALE UNIVERSITY · PI Hooman Kamel, Kevin Navin Sheth · 2019 to 2026
$20.6M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
Social networks and risk of delayed arrival to the hospital during strokeR01MD016178 · NIMHD · BRIGHAM AND WOMEN'S HOSPITAL · PI Amar Dhand, Kevin Navin Sheth · 2022 to 2026
$3.7M
The Recovery in Stroke Using PAP (RISE UP) StudyR01NR018335 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S, SHETH, KEVIN NAVIN · 2019 to 2023
$3.4M
Sequencing Annotation and Functional Analysis in Risk of Intracerebral HemorrhageR01NS103924 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ANDERSON, CHRISTOPHER DAVID · 2018 to 2022
$3.4M
Southern New England Partnership In Stroke Research, Innovation and Treatment (SPIRIT)U24NS107215 · NINDS · YALE UNIVERSITY · PI MARK Jay ALBERTS, Karen L Furie · 2018 to 2026
$3.0M
Improved glyburide therapy via acid- triggered release functional nanoparticles and therapeutic imagingR01NS110721 · NINDS · YALE UNIVERSITY · PI SHETH, KEVIN NAVIN, ZHOU, JIANGBING · 2019 to 2023
$1.9M
Yale Clinical Site: Investigations For Improved Neurological Treatments at Yale (INFINITY)U24NS107136 · NINDS · YALE UNIVERSITY · PI SHETH, KEVIN NAVIN, SPUDICH, SERENA S · 2018 to 2022
$1.7M
Treatment Targets for Inflamed Intracranial Atherosclerosis on Vessel Wall MRIK23NS105924 · NINDS · YALE UNIVERSITY · PI DE HAVENON, ADAM H. · 2019 to 2023
$988k
Intensive Blood Pressure Reduction in Deep Intracerebral HemorrhageR03NS112859 · NINDS · YALE UNIVERSITY · PI FALCONE, GUIDO JOSE, SHETH, KEVIN NAVIN · 2019 to 2020
$84k
American Heart Association-American Stroke Association 24RSSPOST1328228NIA NIH HHS K76 AG059992NIA NIH HHS P30 AG021342NIA NIH HHS T32 AG019134NIMHD NIH HHS R01 MD016178NINDS NIH HHS K23 NS105924NINDS NIH HHS R01 NS103924NINDS NIH HHS R01 NS110721NINDS NIH HHS R03 NS112859NINDS NIH HHS U01 NS106513NINDS NIH HHS U24 NS107136NINDS NIH HHS U24 NS107215NINR NIH HHS R01 NR018335
6 · The paper itself

Abstract

backgroundNontraumatic subarachnoid hemorrhage (SAH) presents a significant health burden, yet the influence of social determinants of health on outcomes remains unclear. This study examines the impact of social determinants of health on outcomes of patients with SAH. METHODS AND

resultsWe conducted a retrospective analysis of prospectively collected data from the GWTG (Get With The Guidelines)-Stroke registry, including patients with SAH across the United States from 2012 to 2021. The role of the Social Deprivation Index (SDI) and adjusted gross income, stratified into tertiles, were assessed. Outcomes included in-hospital death, length of stay, and discharge disposition (good: home/rehabilitation; poor: long-term facility/hospice/death). Covariates included demographics, medical history, vascular risk factors, and SAH severity. Multivariable regressions were used to estimate associations, presenting odds ratios (ORs) and relative risks. Our study comprised 108 090 patients with nontraumatic SAH (mean age, 59.76 years; 61.3% women). The average length of stay was 12.04 days, 55.6% had good discharge disposition, and the overall mortality rate was 15.5%. Analyses showed that a high Social Deprivation Index was associated with reduced odds of a good discharge (unadjusted OR, 0.90 [95% CI, 0.87-0.92]; adjusted OR, 0.87 [95% CI, 0.82-0.92]), while higher adjusted gross income correlated with decreased death (unadjusted OR, 0.94 [95% CI, 0.90-0.97]; adjusted OR, 0.90 [95% CI, 0.83-0.96]). A high Social Deprivation Index was significantly associated with longer length of stay (unadjusted relative risk, 1.06 [95% CI, 1.07-1.26]; adjusted relative risk, 1.03 [95% CI, 1.01-1.13]).

conclusionsSocial determinants of health shape outcomes for patients with SAH, with a clear gradient of impact across socioeconomic levels.

Indexed as

Social Determinants of HealthSubarachnoid HemorrhageAgedFemaleHospital MortalityHumansLength of StayMaleMiddle AgedPatient DischargeRegistriesRetrospective StudiesRisk FactorsUnited Statesadjusted gross incomehealth disparitiessocial deprivation indexsocial determinants of healthsubarachnoid hemorrhage

Identifiers

PMID40194963
PMCPMC12132901

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.