Evidence map›Paper›PMID 40194919›Full record

SynthesisBMJ paediatrics open2025

Faecal impaction in children aged 0-18 years: a systematic review and metanarrative analysis of definitions used.

Morris Gordon, Amber Balda, Samantha Arrizabalo, Vassiliki Sinopoulou, Stephanie Batarseh, Jina Shargawi, Carlo Di Lorenzo, Marc A Benninga, Merit Tabbers, Miguel Saps

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Morris GordonSchool of Medicine, University of Central Lancashire, Preston, UK Mgordon@uclan.ac.uk.ORCID http://orcid.org/0000-0002-1216-5158
Amber BaldaUniversity of Miami Miller School of Medicine, Miami, Florida, USA.
Samantha ArrizabaloUniversity of Miami Miller School of Medicine, Miami, Florida, USA.
Vassiliki SinopoulouSchool of Medicine, University of Central Lancashire, Preston, UK.ORCID http://orcid.org/0000-0002-2831-9406
Stephanie BatarsehUniversity of Central Lancashire, Preston, UK.
Jina ShargawiUniversity of Central Lancashire, Preston, UK.
Carlo Di LorenzoNationwide Children's Hospital, Columbus, Ohio, USA.
Marc A BenningaPediatric Gastroenterology and Nutrition, Emma Childrens' Hospital UMC, Amsterdam, Noord-Holland, The Netherlands.
Merit TabbersPediatric Gastroenterology and Nutrition, Emma Childrens' Hospital UMC, Amsterdam, Noord-Holland, The Netherlands.
Miguel SapsUniversity of Miami Miller School of Medicine, Miami, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFaecal impaction is the result of functional constipation in the majority of cases. Surprisingly, a uniform definition for the term faecal impaction is lacking, leading to heterogeneity across study results.

aimTo conduct a metanarrative systematic review to ascertain how trial studies define faecal impaction among children aged 0-18 years with functional constipation.

methodsWe conducted a systematic metanarrative review to uncover what criteria are used to define faecal impaction and to recommend directions for creating a globally accepted definition. A comprehensive literature search was conducted using prominent databases, including CENTRAL, MEDLINE, Embase, WHO ICTR (international clinical trials registry) and ClinicalTrials.gov. All relevant publications of RCTs on both faecal impaction and functional constipation from inception to June 2024, including children aged 0-18 years without underlying organic aetiology, were included.

results6211 studies were screened, of which 155 were reviewed for eligibility, 76 were included in the review and five are awaiting classification. Seven studies gave an explicit definition, with three referencing a previous consensus definition. 45 studies gave an implicit definition derived from their prescreening or exclusion criteria in a larger piece of research. Clinical assessment was the most common element of definitions, with a mixture of abdominal or rectal assessments reported in 44 studies. A further six studies suggested such clinical assessments are combined with radiographs, and one study reported a definition using radiographs alone. One study reported the duration of symptoms in a definition.

conclusionThere is a clear lack of consensus for defining faecal impaction in children with functional constipation. Despite the clinical, diagnostic and prognostic importance of having a unified definition of faecal impaction, currently there seems to be no universally accepted definition.

Indexed as

ConstipationFecal ImpactionAdolescentChildChild, PreschoolHumansInfantInfant, NewbornGastroenterology

Identifiers

PMID40194919
PMCPMC11977476

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.