Evidence map›Paper›PMID 40194869›Full record

ArticleBMJ open2025

Effectiveness and cost-effectiveness of a home-based functional exercise programme for community-dwelling frail older adults, ACTIVE-AGE@home, provided by professionals and volunteers: protocol of a pragmatic randomised controlled trial.

Dimitri Vrancken, Elke De Smedt, Jade Tambeur, Emma De Keyser, Elise Vanbeuren, David Beckwée, Siddhartha Lieten, Lieven Annemans, Wim Peersman, Dominique Van de Velde and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dimitri VranckenDepartment of Gerontology, Frailty in Ageing Research Group (FRIA), Vrije Universiteit Brussel, Brussels, Belgium.ORCID http://orcid.org/0000-0002-8872-4083
Elke De SmedtDepartment of Geriatrics, Brussels University Hospital, Brussels, Belgium.
Jade TambeurDepartment of Gerontology, Frailty in Ageing Research Group (FRIA), Vrije Universiteit Brussel, Brussels, Belgium.
Emma De KeyserDepartment of Rehabilitation Sciences and Physiotherapy (REVAKI), Research Group MOVANT, University of Antwerp, Wilrijk, Belgium.
Elise VanbeurenDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium.
David BeckwéeDepartment of Rehabilitation Sciences and Physiotherapy (REVAKI), Research Group MOVANT, University of Antwerp, Wilrijk, Belgium.
Siddhartha LietenDepartment of Gerontology, Frailty in Ageing Research Group (FRIA), Vrije Universiteit Brussel, Brussels, Belgium.
Lieven AnnemansDepartment of Public Health and Primary Care, Ghent University, Ghent, Belgium.
Wim PeersmanDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-4276-7408
Dominique Van de VeldeFaculty of Medicine and Health Sciences, Department of Rehabilitation Sciences, Occupational Therapy Research Group, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0001-6982-1075
Patricia De VriendtDepartment of Gerontology, Frailty in Ageing Research Group (FRIA), Vrije Universiteit Brussel, Brussels, Belgium patricia.de.vriendt@vub.be.ORCID http://orcid.org/0000-0003-4861-7838

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between 2020 and 2050, the world's population aged 80 years and over will triple, drastically increasing the prevalence of frailty and associated healthcare costs. Multimodal exercise programmes have proven to be an ideal countermeasure for frailty, but the current Flemish standard of care does not include them. The purpose of this study is to investigate the effect of the home-based exercise programme for frail community-dwelling older adults (>70 years), ACTIVE-AGE@home, on frailty-associated outcomes, when delivered by professionals or volunteers, as well as its cost-effectiveness. A pragmatic randomised controlled trial will be conducted. Participants will be randomised into three parallel groups using permuted block randomisation. There will be two intervention groups: in one group, the intervention is delivered by professionals with a bachelor or masters' degree in physiotherapy, occupational therapy and/or physical education, and in the other by trained volunteers. Both groups will be compared with a control group receiving usual care. Participants (n=195) are community-dwelling

Indexed as

Exercise TherapyFrail ElderlyHome Care ServicesAgedAged, 80 and overBelgiumCost-Benefit AnalysisFemaleHumansIndependent LivingMalePragmatic Clinical Trials as TopicQuality of LifeVolunteersAgedCaregiversExerciseFrailtyHEALTH ECONOMICSRandomized Controlled Trial

Identifiers

PMID40194869
PMCPMC11977484

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.