SynthesisAJNR. American journal of neuroradiology2025
MR Imaging versus Noncontrast CT for Selecting Patients with Acute Ischemic Stroke of Large Vessel Occlusion for Endovascular Thrombectomy: A Systematic Review and Meta-Analysis.
Synthesis in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Deep-learning-based non-contrast CT for detecting acute ischemic stroke: a systematic review and HSROC meta-analysis of patient-level diagnostic accuracy.BMC neurology · 2025Pooled it
- Magnetic resonance imaging and clinical prediction of intracranial atherosclerotic large vessel occlusion in acute ischemic stroke treated with endovascular thrombectomy.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuroimaging in the acute phases after the onset of stroke symptoms is necessary to determine large vessel occlusion presence as well as the extent of the ischemic insult before deeming eligibility for endovascular thrombectomy (EVT). PURPOSE: To evaluate the clinical outcomes in patients with acute ischemic stroke selected for EVT based on initial imaging; NCCT compared with those selected by using MRI. DATA SOURCES: PubMed, Embase, Scopus, and Web of Science were searched from inception until August 2024. STUDY SELECTION: We included observational studies comparing functional independence (mRS 0-2), successful reperfusion (TICI 2b-3), symptomatic intracerebral hemorrhage (sICH), or mortality in patients selected for EVT by using NCCT±CT angiography versus MRI±MR angiography. We excluded studies that used perfusion imaging in their patient selection for EVT. DATA ANALYSIS: Data were pooled by using a random-effects model, and heterogeneity was assessed using I DATA SYNTHESIS: Seven studies ( LIMITATIONS: Our meta-analysis comprised only observational studies, with different populations and imaging protocols limiting the strength of the conclusions.
conclusionsWithin the crucial <6-hour window, the MRI's superior patient selection justifies its use despite longer acquisition times. Beyond 6 hours, the focus should shift to rapid EVT access rather than imaging technique choice as the benefits of MRI diminish.
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