ArticleJournal of cerebrovascular and endovascular neurosurgery2025
The relationship between inflammatory markers and prognosis in patients with ruptured aneurysms treated by endovascular intervention.
Article in Journal of cerebrovascular and endovascular neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aimed to evaluate the prognosis of patients with subarachnoid hemorrhage after anterior communicating artery (Acom) artery aneurysm rupture who underwent endovascular treatment according to inflammatory markers.
methodsA retrospective assessment of medical data revealed 223 consecutive patients who received endovascular Acom artery aneurysmal subarachnoid hemorrhage (SAH) therapy. The study comprised 80 patients, excluding those who had microsurgery following endovascular treatment, those who had diagnostic angiography, patients with ruptured aneurysms at other locations, and those who needed extra surgery. The patients' preoperative electronic medical records were used to collect values of white blood cell (WBC), neutrophil, lymphocyte, C-reactive protein (CRP), neutrophil/lymphocyte ratio (NLR), and CRP/lymphocyte ratio (CLR).
resultsThe study divided patients into two groups based on their modified Rankin Scale (mRS) scores: Group 1 (71.2%) had 57 patients on a scale of 0-2 and Group 2 (28.8%) had 23 patients on a scale of 3-6. Inflammatory markers such as WBC, neutrophils, lymphocytes, CRP, NLR, and CLR levels were higher in Group 2 than in Group 1.
conclusionsOur study evaluated the impact of inflammatory markers (WBC, neutrophils, lymphocytes, CRP, NLR, and CLR) on the prognosis of patients with intracerebral aneurysmal hemorrhage treated endovascularly. Our results indicated that these parameters aligned in their ability to predict the severity of the neurological condition.
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