Evidence map›Paper›PMID 40194463›Full record

ArticleJournal of neurosurgery. Case lessons2025

Screw loosening and subsequent expectoration without anatomical defect following anterior cervical discectomy and fusion for cervical myelopathy: illustrative case.

Nisha L Busch, Peter G Zaki, John Bolger, Nathan Esplin, Cody Woodhouse, Seung W Jeong, Shahed Elhamdani, Chen Xu, Alexander Yu

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Delayed spontaneous expulsion of a stand-alone cervical interbody cage through the oral cavity: a case report and review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nisha L BuschCollege of Medicine, Drexel University, Philadelphia, Pennsylvania.ORCID 0000-0003-4023-7179
Peter G ZakiCollege of Medicine, Drexel University, Philadelphia, Pennsylvania.
John BolgerCollege of Medicine, Drexel University, Philadelphia, Pennsylvania.
Nathan EsplinDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.ORCID 0000-0001-5716-2041
Cody WoodhouseDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.
Seung W JeongDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.
Shahed ElhamdaniDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.
Chen XuDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.
Alexander YuDepartment of Neurosurgery, Allegheny Health Network, Neuroscience Institute, Pittsburgh, Pennsylvania.ORCID 0000-0002-1582-7938

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior cervical discectomy and/or corpectomy with fusion is a standard treatment approach for cervical myelopathy and radiculopathy caused by anterior degenerative and compressive pathology. Serious complications are rare, but esophageal and pharyngeal injuries relating to anterior cervical operations can cause significant morbidity and mortality. The authors present the case of delayed anterior plate screw loosening with eventual expectoration of a screw without anatomical defect. OBSERVATIONS: A 52-year-old male presented to the neurosurgery clinic with cervical myeloradiculopathy. He had severe cervical stenosis with associated myelomalacia. Conservative management failed, and the patient underwent C4 corpectomy and C5-6 and C6-7 anterior cervical discectomy and fusion (ACDF) with anterior plating. He experienced backing out of some of his screws, refused revision, and eventually expectorated his right C3 screw 14 months after surgery with minimal symptoms. He showed no anatomical defects on evaluation and experienced no major morbidity. LESSONS: Hardware expectoration is a rare complication of ACDF. The lack of an esophageal or laryngeal defect could possibly be explained by gradual healing of the injury given the chronicity of his problem. A patient with screw loosening after ACDF should be carefully monitored and evaluated postoperatively due to the potential for significant morbidity and mortality from screw migration and expectoration. https://thejns.org/doi/10.3171/CASE24340.

Indexed as

anterior cervical discectomy and fusioncase reportcervical myelopathyexpectoration

Identifiers

PMID40194463
PMCPMC11976020

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.