Observational studyMedicine2025
Analysis of risk factors for gastrointestinal bleeding in percutaneous coronary intervention patients treated with dual antiplatelet therapy after surgery.
Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis and external validation of a risk model for gastrointestinal bleeding after percutaneous coronary intervention.BMC medicine · 2025Pooled it
- Beyond existing rating scales: development of a novel nomogram for predicting severe clinical bleeding associated with low-molecular-weight heparin in hospitalized medical patients.International journal of clinical pharmacy · 2026Article
- A risk prediction model for gastrointestinal bleeding in coronary heart disease patients undergoing dual antiplatelet therapy after percutaneous coronary intervention.Pakistan journal of medical sciences · 2025Article
- Bleeding in Antiplatelet Therapy: A Narrative Review of Clinical Evidence and the Roles of Pharmacists and Nurses.Reviews in cardiovascular medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) is key to preventing thrombosis. However, the use of DAPT is strongly associated with an increased risk of Gastrointestinal Bleeding, which not only affects patient recovery but also increases the healthcare burden. This study aims to determine the influence of past medical history and factors during hospitalization on the development of postoperative GIB in patients undergoing PCI with DAPT. A total of 380 patients were collected in this study. A total of 42 patients developed GIB during the 1-year follow-up period. Preoperative and postoperative clinical data and past medical history of patients were collected to study the correlates affecting the occurrence of GIB in the postoperative period in patients undergoing PCI with DAPT and to establish a prediction model. Single-factor logistic regression analysis showed: gender, age, past history of bleeding, past history of cancer or tumor, smoking history, history of heart failure, history of PPI use, renal insufficiency, and hypoproteinemia are potential risk factors that may influence the occurrence of GIB postoperatively in patients undergoing DAPT for PCI, P < .2. The data obtained were further included in multi-factor logistic regression analysis: gender (female), past history of bleeding, past history of cancer or tumor, smoking history, heart failure, renal insufficiency were independent risk factors influencing the occurrence of GIB postoperatively in PCI patients undergoing DAPT, P < .05. The findings of this study confirm that gender (female), past history of bleeding, past history of cancer or tumor, smoking history, heart failure and renal insufficiency are independent risk factors for the development of GIB postoperatively in PCI patients undergoing DAPT.
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Registered trials
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