Evidence map›Paper›PMID 40193380›Full record

ArticlePloS one2025

Deciphering insights into commercial Myrrh species authenticity from the psbA-trsnH genetic region.

Changhong Cao, Wenting Zhong, Feng Gao, Ying Zhang, Zhiguo Ma, Hui Cao, Menghua Wu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Changhong CaoLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Wenting ZhongLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Feng GaoLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Ying ZhangLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Zhiguo MaLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Hui CaoLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.
Menghua WuLingnan Traditional Chinese Medicine Research Centre, School of Pharmaceutical Sciences, Jinan University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-2947-0148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe genetic analysis, particularly focusing on the psbA-trnH region, aims to tackle the challenges linked to myrrh identification and improve quality control in medicinal and aromatic plant sectors. This process reveals the genetic diversity inherent in myrrh species, identifies adulterants, and assesses consistency with pharmacopoeia-designated species.

methodsA meticulous investigation was conducted, involving twenty-five myrrh samples sourced from diverse origins and one adulterant sample. The methodology encompassed precise execution of DNA extraction, PCR amplification targeting the psbA-trnH region, sequencing, and subsequent data analysis. Additionally, the integration of GenBank data was employed to enrich the genetic analysis.

resultsThe psbA-trnH region demonstrated 100% amplification efficiency across all myrrh samples, accurately identifying three distinct species-Commiphora gileadensis, Commiphora myrrha, and Commiphora edulis. Only 8% of samples aligned with pharmacopoeia-specified species, revealing a significant misalignment. The identified adulterant, Liquidambar formosana, underscored the efficacy of the genetic approach. Genetic distances and haplotype analysis offered insights into myrrh species diversity. Intraspecific and interspecific distances highlighted the discriminatory potential of the psbA-trnH region. A phylogenetic tree illustrated distinct genetic clusters among Commiphora species and Liquidambar formosana.

conclusionsIt affirms the robustness of the psbA-trnH region for authenticating myrrh and emphasizes the necessity of adapting pharmacopoeial standards to accurately mirror genetic diversity. An avenue for exploring therapeutic variations within myrrh species and advocates collaboration among researchers, regulatory agencies, and industry stakeholders to fortify comprehensive quality management measures within the context of agronomy-focused herbal products.

Indexed as

CommiphoraDNA, PlantGenetic VariationPhylogenyDNA, Plant

Identifiers

PMID40193380
PMCPMC11975096

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