Trial reportPloS one2025
Comparison between bupivacaine-lidocaine, dexamethasone mixture and bupivacaine alone for motor recovery after axillary brachial plexus block in distal radius surgery: A prospective randomized trial.
Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProlonged motor block, known as "dead arm," which can cause patient discomfort and anxiety, is a serious concern that is often overlooked in ambulatory surgery, particularly in elderly patients. The purpose of this study was to examine the recovery time of motor blockade with bupivacaine and a mixture of bupivacaine-lidocaine-dexamethasone in axillary brachial plexus block.
methodsA prospective, randomized, double-blinded controlled trial was conducted with 70 patients scheduled for distal end radius fixation under axillary brachial plexus block. A local anesthetic mixture group (LA-mixture group) received a 21 ml mixture of 0.2% bupivacaine with 1.2% lidocaine and 5 mg of dexamethasone (n = 35). A bupivacaine group received 20 ml of 0.5% bupivacaine with 1 ml of normal saline (n = 35). The primary outcome was the duration of the motor blockade. Secondary outcomes included the duration of sensory blockade, postoperative pain score, and the incidence of rebound pain.
resultsThe demographic data were similar between the two groups. The mean times for recovery of hand grips and sensation were 13.5 ± 7.3 and 12.6 ± 6.2 hours in the LA-mixture group and 15.3 ± 6.7 and 14.6 ± 6.2 hours in the bupivacaine group. Pain scores were not significantly different between the two groups, but the incidence of rebound pain was lower in the LA-mixture group (8.6% and 28.6%, p = 0.031).
conclusionThe bupivacaine-lidocaine, dexamethasone mixture failed to enhance motor recovery compared to 0.5% bupivacaine alone. However, patients in the mixture group appeared to experience a lower incidence of rebound pain.
trial registrationThai Clinical Trials Registry TCTR20200114003.
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