Evidence map›Paper›PMID 40193310›Full record

ArticleJournal of visualized experiments : JoVE2025

Imaging Ca2+ Signals in Small Pulmonary Veins at Physiological Intraluminal Pressures.

Yen-Lin Chen, Kyosuke Kazama, Vihaan Vattipally, Swapnil K Sonkusare

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yen-Lin ChenRobert M. Berne Cardiovascular Research Center, University of Virginia.
Kyosuke KazamaRobert M. Berne Cardiovascular Research Center, University of Virginia.
Vihaan VattipallyRobert M. Berne Cardiovascular Research Center, University of Virginia.
Swapnil K SonkusareRobert M. Berne Cardiovascular Research Center, University of Virginia; Department of Molecular Physiology and Biological Physics, University of Virginia; swapnil.sonkusare@virginia.edu.

Funding

Paracrine TNF signaling impairs endothelial TRPV4 microdomains in obesityR01HL142808 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$4.4M
Flow-Activated Calcium Signaling Microdomains in Small Pulmonary ArteriesR01HL146914 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2019 to 2026
$3.8M
Role of TRPV4 channel signaling in lung ischemia-reperfusion injuryR01HL157407 · NHLBI · UNIVERSITY OF VIRGINIA · PI LAUBACH, VICTOR E, SONKUSARE, SWAPNIL K. · 2021 to 2024
$2.7M
Novel Calcium Signaling Nanodomains in Vascular Smooth Muscle CellsR01HL167208 · NHLBI · UNIVERSITY OF VIRGINIA · PI Swapnil K. Sonkusare · 2023 to 2026
$2.1M
Lymphatic Endothelial Piezo1-TRPV4 Channel Signaling in ObesityK99DK138271 · NIDDK · UNIVERSITY OF VIRGINIA · PI CHEN, YEN-LIN · 2024 to 2025
$180k
NHLBI NIH HHS R01 HL142808NHLBI NIH HHS R01 HL146914NHLBI NIH HHS R01 HL157407NHLBI NIH HHS R01 HL167208NIDDK NIH HHS K99 DK138271
6 · The paper itself

Abstract

Pulmonary veins (PVs) carry oxygen-rich blood from the lungs back to the left heart, thus serving an important function in the delivery of oxygen-rich blood to vital organs. However, most studies of pulmonary vasculature have focused on pulmonary arteries and capillaries under normal and disease conditions. Ca

Indexed as

CalciumCalcium SignalingPulmonary VeinsAnimalsMiceMicroscopy, ConfocalRyanodine Receptor Calcium Release ChannelCalciumRyanodine Receptor Calcium Release Channel

Identifiers

PMID40193310
PMCPMC12087461

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.