ArticleBiological trace element research2025
Sex-Specific Association Between Serum Zinc Concentration and Risk of Developing Type 2 Diabetes in Individuals with Isolated Impaired Fasting Glucose: A Prospective Cohort.
Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Association between serum zinc levels and new-onset hypertension: A 5-year retrospective cohort study.Medicine · 2026Article
- Risk of Zinc Deficiency from Urinary Zinc Loss Induced by Antihypertensive Drugs: A Narrative Review.Biological trace element research · 2026Review
- Risk of Zinc Deficiency from Urinary Zinc Loss Induced by Antihypertensive Drugs: A Narrative Review.Biological trace element research · 2026Review
- Reference Values for Biochemical Analytes in An Iranian Population: The Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2026Review
- Zinc deficiency in patients with type 2 diabetes increases risk of cardiovascular diseases: Tehran Lipid and Glucose Study.BMC cardiovascular disorders · 2026Article
- Serum Zinc Levels in Early Life and Risk of Elevated Carotid Intima-Media Thickness: An 8-Year Prospective Study.Cardiovascular toxicology · 2026Article
- Serum Zinc Levels in Early Life and Risk of Elevated Carotid Intima-Media Thickness: An 8-Year Prospective Study.Cardiovascular toxicology · 2026Article
- Rethinking Zinc Requirements in Diabetes Mellitus: Comprehensive Review of Experimental and Clinical Studies Evidence.Biological trace element research · 2026Review
- Rethinking Zinc Requirements in Diabetes Mellitus: Comprehensive Review of Experimental and Clinical Studies Evidence.Biological trace element research · 2026Review
- Prediabetes in Transition: Insights from the Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2025Review
- Zinc and Adipose Organ Dysfunction: Molecular Insights into Obesity and Metabolic Disorders.Current nutrition reports · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This cohort study investigated the possible association between serum zinc (SZn) concentration and risk of progression to type 2 diabetes (T2D) in subjects with isolated impaired fasting glucose (iIFG). SZn concentrations were measured using flame atomic absorption spectrometry (FAAS) in 585 subjects with iIFG (mean age of 50.2 ± 13.9 y, and 52.1% were men) at baseline (2009-2011), and they were followed for developing T2D up to 2017. A univariate unrestricted regression spline was used to assess the potential non-linear association and identify the best placement of knots of SZn in relation to the incidence of T2D. Multivariable Cox proportional hazard models were used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of T2D across the tertile categories of SZn (< 92, 92-122, and ≥ 122 μg/dL). Over a median of 6-year follow-up, 17.8% of subjects developed T2D (16.1% and 19.6% in men and women, respectively). A non-linear association was observed between SZn and the incidence of T2D (P
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Registered trials
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